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Catalog Number:
40351
CAS Number:
109299-78-7
5-Pyrimidylboronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
Pyrimidinyl-5-boronic acid
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$18.53 /100MG
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Product Information

5-Pyrimidylboronic acid is a versatile compound widely recognized for its applications in medicinal chemistry and organic synthesis. This boronic acid derivative features a pyrimidine ring, which enhances its reactivity and makes it an essential building block in the development of pharmaceuticals, particularly in the synthesis of kinase inhibitors and other biologically active molecules. Its unique ability to form reversible covalent bonds with diols and other nucleophiles allows for the creation of complex molecular architectures, making it invaluable in drug discovery and development processes.

In addition to its role in pharmaceutical applications, 5-Pyrimidylboronic acid is also utilized in materials science for the preparation of functionalized polymers and in the development of sensors. Its compatibility with various coupling reactions, such as Suzuki-Miyaura cross-coupling, further expands its utility in synthetic organic chemistry. Researchers and industry professionals benefit from its high reactivity and selectivity, enabling the efficient construction of diverse chemical libraries. Overall, 5-Pyrimidylboronic acid stands out as a crucial reagent for advancing research and innovation across multiple fields.

Synonyms
Pyrimidinyl-5-boronic acid
CAS Number
109299-78-7
Purity
95 - 105% (Assay by titration)
Molecular Formula
C4H5BN2O2
Molecular Weight
123.91
MDL Number
MFCD03002366
PubChem ID
2795193
Melting Point
114 °C (Lit.)
Appearance
White to light orange to green powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Pyrimidinyl-5-boronic acid
CAS Number
109299-78-7
Purity
95 - 105% (Assay by titration)
Molecular Formula
C4H5BN2O2
Molecular Weight
123.91
MDL Number
MFCD03002366
PubChem ID
2795193
Melting Point
114 °C (Lit.)
Appearance
White to light orange to green powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Pyrimidylboronic acid is widely utilized in research focused on:

  • Drug Development: This compound plays a crucial role in the synthesis of various pharmaceuticals, particularly in the development of targeted therapies for cancer. Its ability to form stable complexes with biomolecules enhances drug efficacy.
  • Bioconjugation: It is commonly used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules. This is particularly useful in creating targeted drug delivery systems and diagnostic tools.
  • Organic Synthesis: In organic chemistry, it serves as a versatile building block for synthesizing complex organic compounds. Its unique properties make it an excellent choice for creating new materials with specific functionalities.
  • Sensor Technology: The compound is applied in the development of chemical sensors, particularly for detecting glucose levels in diabetic patients. Its sensitivity and selectivity make it a valuable component in biosensor design.
  • Material Science: It is utilized in the fabrication of advanced materials, such as polymers and nanomaterials, that have applications in electronics and photonics, enhancing the performance of devices.

Citations