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Catalog Number:
40349
CAS Number:
247564-73-4
2,3,5-Trifluorophenylboronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
2,3,5-Trifluorobenzeneboronic acid
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Product Information

2,3,5-Trifluorophenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its ability to form stable complexes with diols, making it an essential reagent in the development of various pharmaceuticals and agrochemicals. Its unique trifluoromethyl group enhances its reactivity and selectivity in cross-coupling reactions, such as Suzuki-Miyaura coupling, which is pivotal in constructing complex organic molecules. Researchers appreciate its role in the synthesis of biologically active compounds, including potential drug candidates, due to its compatibility with a range of functional groups.

In addition to its applications in synthetic chemistry, 2,3,5-Trifluorophenylboronic acid is also employed in the development of sensors and materials science, where its boron functionality can be leveraged for creating innovative polymeric materials. Its distinctive properties, such as thermal stability and solubility in various solvents, make it an attractive choice for both academic research and industrial applications. This compound stands out for its efficiency in facilitating reactions that lead to high yields of desired products, making it a valuable asset for chemists and researchers alike.

Synonyms
2,3,5-Trifluorobenzeneboronic acid
CAS Number
247564-73-4
Purity
95 - 105% (Assay by titration)
Molecular Formula
C6H4BF3O2
Molecular Weight
175.9
MDL Number
MFCD01863166
PubChem ID
4078843
Melting Point
221 °C (dec.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
2,3,5-Trifluorobenzeneboronic acid
CAS Number
247564-73-4
Purity
95 - 105% (Assay by titration)
Molecular Formula
C6H4BF3O2
Molecular Weight
175.9
MDL Number
MFCD01863166
PubChem ID
4078843
Melting Point
221 °C (dec.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,3,5-Trifluorophenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a key building block in the synthesis of various organic molecules, particularly in the development of pharmaceuticals and agrochemicals, enhancing the efficiency of chemical reactions.
  • Drug Development: Its unique properties allow for the modification of drug candidates, improving their efficacy and selectivity, which is crucial in the pharmaceutical industry for creating more effective treatments.
  • Materials Science: Used in the fabrication of advanced materials, it contributes to the development of polymers and coatings with enhanced properties, such as increased durability and resistance to environmental factors.
  • Bioconjugation: This compound is valuable in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, facilitating research in biotechnology and diagnostics.
  • Fluorine Chemistry: Its trifluoromethyl group provides unique reactivity, making it a useful tool in fluorine chemistry, which is essential for creating compounds with improved biological activity and stability.

Citations