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Catalog Number:
40342
CAS Number:
212386-71-5
4-Ethoxy-2,3-difluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
4-Ethoxy-2,3-difluorobenzeneboronic acid
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Product Information

4-Ethoxy-2,3-difluorophenylboronic acid is a versatile compound known for its unique boronic acid functionality, making it an essential reagent in organic synthesis and medicinal chemistry. This compound features a difluorophenyl group, which enhances its reactivity and selectivity in various chemical reactions, particularly in Suzuki-Miyaura cross-coupling reactions. Researchers and industry professionals can leverage its properties for the development of complex organic molecules, including pharmaceuticals and agrochemicals. Its ability to form stable complexes with diols also makes it valuable in the synthesis of boron-containing compounds, which are crucial in various applications, such as drug discovery and material science.

In addition to its synthetic utility, 4-Ethoxy-2,3-difluorophenylboronic acid stands out due to its favorable solubility characteristics and compatibility with a range of solvents, which can streamline laboratory processes. This compound is particularly beneficial for those working in the field of medicinal chemistry, where it can facilitate the creation of novel therapeutic agents. Its unique structure and reactivity profile provide researchers with a powerful tool for advancing their work in organic synthesis and drug development.

Synonyms
4-Ethoxy-2,3-difluorobenzeneboronic acid
CAS Number
212386-71-5
Purity
97 - 105% (Assay by titration)
Molecular Formula
C8H9BF2O3
Molecular Weight
201.96
MDL Number
MFCD09258743
PubChem ID
15135235
Melting Point
154 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-Ethoxy-2,3-difluorobenzeneboronic acid
CAS Number
212386-71-5
Purity
97 - 105% (Assay by titration)
Molecular Formula
C8H9BF2O3
Molecular Weight
201.96
MDL Number
MFCD09258743
PubChem ID
15135235
Melting Point
154 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Ethoxy-2,3-difluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of targeted cancer therapies, enhancing drug efficacy and specificity.
  • Organic Synthesis: It is employed in cross-coupling reactions, such as Suzuki-Miyaura coupling, allowing chemists to create complex organic molecules efficiently, which is essential in materials science and agrochemicals.
  • Bioconjugation: The boronic acid functionality enables selective binding to diols, making it useful in bioconjugation techniques for drug delivery systems and diagnostic applications, improving the precision of targeting in biological systems.
  • Material Science: This compound can be used to modify surfaces and create functional materials, such as sensors and catalysts, which are crucial in developing advanced technologies for electronics and environmental applications.
  • Research in Chemical Biology: It plays a role in studying protein interactions and cellular processes, providing insights into biochemical pathways and potential therapeutic targets, thus aiding in the advancement of biomedical research.

Citations