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Catalog Number:
40338
CAS Number:
226396-32-3
2,3,4-Trifluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
2,3,4-Trifluorobenzeneboronic acid
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Product Information

2,3,4-Trifluorophenylboronic acid is a versatile and valuable compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its unique trifluoromethyl group, which enhances its reactivity and selectivity in various chemical reactions. It serves as an essential building block in the development of pharmaceuticals, agrochemicals, and advanced materials. Researchers often employ 2,3,4-Trifluorophenylboronic acid in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds that are crucial in constructing complex molecular architectures. Its ability to form stable complexes with diols also makes it a key player in the development of sensors and catalysts.

The compound's distinctive properties, such as its high thermal stability and solubility in organic solvents, further enhance its applicability in diverse fields. In the pharmaceutical industry, it has been instrumental in the synthesis of biologically active compounds, showcasing its potential in drug discovery and development. With its growing relevance in cutting-edge research, 2,3,4-Trifluorophenylboronic acid stands out as a compound that not only meets the demands of modern chemistry but also opens new avenues for innovation.

Synonyms
2,3,4-Trifluorobenzeneboronic acid
CAS Number
226396-32-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H4BF3O2
Molecular Weight
175.9
MDL Number
MFCD01863168
PubChem ID
2783280
Melting Point
235 °C (Lit.)
Appearance
White to light orange to green powder
Conditions
Store at RT
General Information
Synonyms
2,3,4-Trifluorobenzeneboronic acid
CAS Number
226396-32-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H4BF3O2
Molecular Weight
175.9
MDL Number
MFCD01863168
PubChem ID
2783280
Melting Point
235 °C (Lit.)
Appearance
White to light orange to green powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,3,4-Trifluorophenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile building block in the synthesis of various organic molecules, particularly in the development of pharmaceuticals and agrochemicals.
  • Medicinal Chemistry: It plays a crucial role in drug discovery, especially in the design of inhibitors for enzymes and receptors, enhancing the efficacy of therapeutic agents.
  • Materials Science: The compound is used in the development of advanced materials, including polymers and coatings, providing unique properties due to its fluorine content.
  • Bioconjugation: It is applied in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in diagnostics and therapeutic applications.
  • Environmental Chemistry: Researchers utilize it to study environmental pollutants and their interactions, helping in the development of strategies for pollution control and remediation.

Citations