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Catalog Number:
40331
CAS Number:
870779-02-5
2,6-Difluoro-3-methoxyphenylboronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
2,6-Difluoro-3-methoxybenzeneboronic acid
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Product Information

2,6-Difluoro-3-methoxyphenylboronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its unique ability to form stable complexes with various substrates, making it an essential reagent in Suzuki-Miyaura cross-coupling reactions. Its fluorinated structure enhances its reactivity and selectivity, which is particularly beneficial in the development of pharmaceuticals and agrochemicals. Researchers have utilized this compound to synthesize complex organic molecules, including biologically active compounds, thereby streamlining the drug discovery process.

Additionally, 2,6-Difluoro-3-methoxyphenylboronic acid exhibits excellent solubility in common organic solvents, facilitating its application in diverse reaction conditions. Its compatibility with various functional groups allows for the efficient modification of existing compounds, making it a valuable tool for chemists in both academic and industrial settings. With its robust performance in synthetic applications, this boronic acid derivative stands out as a preferred choice for professionals seeking reliable and effective reagents in their research and development projects.

Synonyms
2,6-Difluoro-3-methoxybenzeneboronic acid
CAS Number
870779-02-5
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H7BF2O3
Molecular Weight
187.94
MDL Number
MFCD06657880
PubChem ID
2783131
Melting Point
114 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
2,6-Difluoro-3-methoxybenzeneboronic acid
CAS Number
870779-02-5
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H7BF2O3
Molecular Weight
187.94
MDL Number
MFCD06657880
PubChem ID
2783131
Melting Point
114 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,6-Difluoro-3-methoxyphenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and other diseases due to its ability to form stable complexes with biomolecules.
  • Material Science: It is used in the creation of advanced materials, such as polymers and nanomaterials, enhancing properties like conductivity and mechanical strength, which are crucial in electronics and engineering applications.
  • Organic Synthesis: The compound acts as a versatile reagent in cross-coupling reactions, facilitating the formation of carbon-carbon bonds, which is essential in the synthesis of complex organic molecules.
  • Bioconjugation: Its boronic acid functionality allows for selective binding to diols in biomolecules, making it valuable in bioconjugation techniques for labeling and drug delivery systems.
  • Environmental Chemistry: This chemical is also explored for its potential in environmental applications, such as the detection and removal of pollutants, owing to its reactivity and ability to form stable complexes with various environmental contaminants.

Citations