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Catalog Number:
40327
CAS Number:
149507-36-8
4-Methoxy-3-(trifluoromethyl)phenylboronic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
4-Methoxy-3-(trifluoromethyl)benzeneboronic acid
Documents
$62.59 /200MG
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Product Information

4-Methoxy-3-(trifluoromethyl)phenylboronic acid is a versatile boronic acid derivative known for its unique trifluoromethyl group, which enhances its reactivity and selectivity in various chemical reactions. This compound is particularly valuable in the field of organic synthesis, where it serves as a key building block for the development of pharmaceuticals and agrochemicals. Its ability to participate in Suzuki-Miyaura cross-coupling reactions makes it an essential reagent for creating complex molecules with precision. Researchers and industry professionals can leverage its properties to synthesize biologically active compounds, contributing to advancements in drug discovery and development.

Additionally, 4-Methoxy-3-(trifluoromethyl)phenylboronic acid exhibits excellent solubility in organic solvents, facilitating its use in diverse reaction conditions. Its trifluoromethyl group not only improves the electronic properties of the compound but also enhances the stability of the resulting products. This makes it a preferred choice for chemists looking to optimize reaction yields and selectivity. With its broad applicability and unique features, this boronic acid derivative stands out as a valuable tool in modern synthetic chemistry.

Synonyms
4-Methoxy-3-(trifluoromethyl)benzeneboronic acid
CAS Number
149507-36-8
Purity
≥ 98% (HPLC)
Molecular Formula
C8H8BF3O3
Molecular Weight
219.95
MDL Number
MFCD07363790
PubChem ID
17750052
Melting Point
202 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-Methoxy-3-(trifluoromethyl)benzeneboronic acid
CAS Number
149507-36-8
Purity
≥ 98% (HPLC)
Molecular Formula
C8H8BF3O3
Molecular Weight
219.95
MDL Number
MFCD07363790
PubChem ID
17750052
Melting Point
202 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Methoxy-3-(trifluoromethyl)phenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, enabling the development of new drugs and crop protection agents.
  • Cross-Coupling Reactions: It is commonly used in Suzuki-Miyaura coupling reactions, which are essential for forming carbon-carbon bonds in organic chemistry, making it invaluable for researchers in synthetic chemistry.
  • Fluorinated Compounds: The trifluoromethyl group enhances the bioactivity of compounds. This property is particularly beneficial in medicinal chemistry, where increased potency and selectivity are desired.
  • Analytical Chemistry: This chemical can be employed in the development of sensors and probes due to its unique reactivity, aiding in the detection of various analytes in environmental and biological samples.
  • Material Science: It is used in the modification of polymers and materials, improving their properties for applications in electronics and coatings, thus enhancing performance and durability.

Citations