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Catalog Number:
40325
CAS Number:
871329-52-1
(2-Chloro-3-fluorophenyl)boronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
2-Chloro-3-fluorobenzeneboronic acid
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Product Information

(2-Chloro-3-fluorophenyl)boronic acid is a versatile compound widely utilized in organic synthesis and pharmaceutical research. Known for its unique reactivity, this boronic acid derivative serves as a crucial building block in the development of various biologically active molecules. Its ability to participate in Suzuki-Miyaura cross-coupling reactions makes it invaluable for creating complex carbon frameworks, which are essential in the synthesis of agrochemicals and pharmaceuticals. Researchers appreciate its effectiveness in forming stable bonds with a variety of substrates, enabling the efficient construction of intricate molecular architectures.

In addition to its synthetic applications, (2-Chloro-3-fluorophenyl)boronic acid is also recognized for its potential in medicinal chemistry, particularly in the development of targeted therapies. Its specific structural features allow for the modification of drug candidates, enhancing their efficacy and selectivity. This compound stands out among similar boronic acids due to its favorable reactivity profile and the ability to introduce functional groups that can improve the pharmacological properties of therapeutic agents.

Synonyms
2-Chloro-3-fluorobenzeneboronic acid
CAS Number
871329-52-1
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD07363741
PubChem ID
22309459
Melting Point
84 °C (Lit.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
2-Chloro-3-fluorobenzeneboronic acid
CAS Number
871329-52-1
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD07363741
PubChem ID
22309459
Melting Point
84 °C (Lit.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(2-Chloro-3-fluorophenyl)boronic acid is widely utilized in research focused on:

  • Drug Development: This compound serves as a crucial building block in the synthesis of pharmaceuticals, particularly in the development of targeted cancer therapies. Its unique structure allows for the modification of drug candidates to enhance efficacy and reduce side effects.
  • Material Science: It plays a significant role in the creation of advanced materials, such as polymers and nanomaterials. Researchers leverage its boronic acid functionality to develop materials with tailored properties for electronics and sensors.
  • Organic Synthesis: In organic chemistry, this compound is used in cross-coupling reactions, such as Suzuki-Miyaura coupling, which is essential for forming carbon-carbon bonds in complex organic molecules.
  • Bioconjugation: The ability to form stable bonds with biomolecules makes it valuable in bioconjugation applications, aiding in the development of targeted drug delivery systems and diagnostic tools.
  • Agricultural Chemistry: It is also explored in the formulation of agrochemicals, where its properties can enhance the effectiveness of herbicides and pesticides, contributing to more sustainable agricultural practices.

Citations