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Catalog Number:
40323
CAS Number:
468718-30-1
5-Cyano-2-fluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
5-Cyano-2-fluorobenzeneboronic acid
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Product Information

5-Cyano-2-fluorophenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its unique ability to form stable complexes with diols, making it an essential reagent in the development of various pharmaceuticals and agrochemicals. Its distinctive cyano and fluorine substituents enhance its reactivity and selectivity in cross-coupling reactions, particularly in Suzuki-Miyaura coupling, which is pivotal for constructing complex organic frameworks. Researchers have leveraged this compound in the synthesis of biologically active molecules, including potential anti-cancer agents and other therapeutic compounds, showcasing its relevance in drug discovery and development.

In addition to its applications in pharmaceutical synthesis, 5-Cyano-2-fluorophenylboronic acid is also valuable in materials science, particularly in the development of functionalized polymers and advanced materials. Its ability to facilitate the formation of carbon-carbon bonds under mild conditions makes it a preferred choice for chemists aiming to create innovative materials with tailored properties. With its broad applicability and unique features, this compound stands out as a crucial tool for researchers and industry professionals seeking to advance their projects efficiently.

Synonyms
5-Cyano-2-fluorobenzeneboronic acid
CAS Number
468718-30-1
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H5BFNO2
Molecular Weight
164.93
MDL Number
MFCD03095147
PubChem ID
2783361
Melting Point
> 300 °C
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
5-Cyano-2-fluorobenzeneboronic acid
CAS Number
468718-30-1
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H5BFNO2
Molecular Weight
164.93
MDL Number
MFCD03095147
PubChem ID
2783361
Melting Point
> 300 °C
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Cyano-2-fluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound is used in the synthesis of various pharmaceutical agents, particularly in the development of targeted cancer therapies. Its ability to form stable complexes with biomolecules enhances drug efficacy.
  • Organic Synthesis: It serves as a key intermediate in organic synthesis, allowing chemists to create complex molecules through Suzuki coupling reactions, which are essential in producing fine chemicals and agrochemicals.
  • Material Science: The compound is employed in the creation of advanced materials, including polymers and nanomaterials, which have applications in electronics and coatings due to their unique properties.
  • Bioconjugation: It is used in bioconjugation techniques to attach biomolecules to surfaces or other molecules, facilitating the development of biosensors and diagnostic tools.
  • Research in Chemical Biology: This chemical plays a role in studying enzyme mechanisms and protein interactions, providing insights that can lead to novel therapeutic approaches.

Citations