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Catalog Number:
40321
CAS Number:
214210-21-6
3-Cyano-4-fluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
3-Cyano-4-fluorobenzeneboronic acid
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Product Information

3-Cyano-4-fluorophenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its ability to form stable complexes with diols, making it an essential reagent in the development of various pharmaceuticals and agrochemicals. Its unique cyano and fluorine substituents enhance its reactivity and selectivity, allowing for precise modifications in complex molecular architectures. Researchers have successfully employed this compound in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds, which are pivotal in the synthesis of advanced materials and biologically active compounds.

In addition to its synthetic applications, 3-Cyano-4-fluorophenylboronic acid has shown promise in the field of diagnostics and sensor technology, where its ability to interact with specific biomolecules can be harnessed for the development of innovative detection systems. The compound's stability and functional versatility make it a valuable asset for researchers seeking to explore new avenues in drug discovery and material science. With its broad range of applications, this boronic acid is an indispensable tool for professionals aiming to push the boundaries of chemical research and development.

Synonyms
3-Cyano-4-fluorobenzeneboronic acid
CAS Number
214210-21-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H5BFNO2
Molecular Weight
164.93
MDL Number
MFCD03095130
PubChem ID
2757964
Melting Point
> 300 °C
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
3-Cyano-4-fluorobenzeneboronic acid
CAS Number
214210-21-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H5BFNO2
Molecular Weight
164.93
MDL Number
MFCD03095130
PubChem ID
2757964
Melting Point
> 300 °C
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-Cyano-4-fluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-cancer agents. Its unique structure allows for targeted modifications that enhance drug efficacy.
  • Organic Synthesis: It is an important reagent in cross-coupling reactions, such as Suzuki-Miyaura coupling, which is widely used in the creation of complex organic molecules. This application is crucial for researchers in the fields of materials science and organic chemistry.
  • Fluorescent Probes: The compound can be utilized in the development of fluorescent probes for biological imaging. Its ability to bind selectively to certain biomolecules makes it valuable in cellular and molecular biology studies.
  • Sensor Technology: 3-Cyano-4-fluorophenylboronic acid is effective in the fabrication of sensors for detecting sugars and other biomolecules. This application is particularly relevant in the food industry and medical diagnostics.
  • Environmental Monitoring: The compound can be used in analytical chemistry for the detection of pollutants. Its sensitivity and specificity make it suitable for monitoring environmental contaminants, aiding in compliance with regulatory standards.

Citations