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Catalog Number:
40320
CAS Number:
352535-83-2
5-Chloro-2-fluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
5-Chloro-2-fluorobenzeneboronic acid
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Product Information

5-Chloro-2-fluorophenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Its unique combination of chlorine and fluorine substituents enhances its reactivity and selectivity, allowing researchers to create targeted compounds with improved efficacy.

In addition to its applications in synthetic chemistry, 5-Chloro-2-fluorophenylboronic acid is also employed in the development of novel materials and sensors, showcasing its adaptability across various fields. Its stability under standard laboratory conditions and compatibility with a range of functional groups make it an ideal choice for researchers looking to streamline their synthetic pathways. This compound not only facilitates efficient synthesis but also opens avenues for innovation in drug discovery and material science.

Synonyms
5-Chloro-2-fluorobenzeneboronic acid
CAS Number
352535-83-2
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD05664225
PubChem ID
3718925
Melting Point
182 - 188 °C
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
5-Chloro-2-fluorobenzeneboronic acid
CAS Number
352535-83-2
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD05664225
PubChem ID
3718925
Melting Point
182 - 188 °C
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Chloro-2-fluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound plays a crucial role in synthesizing various pharmaceuticals, particularly in the development of targeted cancer therapies. Its ability to form stable complexes with biomolecules enhances drug efficacy.
  • Organic Synthesis: It serves as a key building block in organic chemistry, allowing researchers to create complex molecules through Suzuki coupling reactions. This is particularly beneficial in the production of agrochemicals and fine chemicals.
  • Material Science: The compound is used in the development of advanced materials, including polymers and nanomaterials, which can be applied in electronics and coatings due to their unique properties.
  • Bioconjugation: It is utilized in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in creating biosensors and diagnostic tools.
  • Research in Catalysis: The compound is explored in catalytic processes, enhancing reaction rates and selectivity, which is vital for efficient chemical manufacturing and reducing waste in industrial processes.

Citations