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Catalog Number:
40318
CAS Number:
151169-67-4
4-Chloro-3-nitrophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
4-Chloro-3-nitrobenzeneboronic acid
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Product Information

4-Chloro-3-nitrophenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valuable for its ability to form stable complexes with diols, making it an essential reagent in the development of various pharmaceuticals and agrochemicals. Its unique structure allows for applications in Suzuki-Miyaura cross-coupling reactions, which are crucial for constructing complex organic molecules. Researchers appreciate its role in the synthesis of biologically active compounds, including potential anti-cancer agents and other therapeutic molecules.

In addition to its synthetic utility, 4-Chloro-3-nitrophenylboronic acid is recognized for its effectiveness in sensor technology, particularly in the detection of carbohydrates and other biomolecules. Its ability to selectively bind to specific targets enhances its application in biosensors, providing a reliable method for monitoring biological processes. With its combination of reactivity and specificity, this compound stands out as a valuable tool for researchers and industry professionals looking to innovate in chemical synthesis and analytical applications.

Synonyms
4-Chloro-3-nitrobenzeneboronic acid
CAS Number
151169-67-4
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClNO4
Molecular Weight
201.37
MDL Number
MFCD02258950
PubChem ID
5006651
Melting Point
275 °C (dec.)
Appearance
White to light yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-Chloro-3-nitrobenzeneboronic acid
CAS Number
151169-67-4
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClNO4
Molecular Weight
201.37
MDL Number
MFCD02258950
PubChem ID
5006651
Melting Point
275 °C (dec.)
Appearance
White to light yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Chloro-3-nitrophenylboronic acid is widely utilized in research focused on:

  • Drug Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-cancer agents due to its ability to modify biological targets effectively.
  • Organic Synthesis: It is employed in cross-coupling reactions, such as Suzuki-Miyaura coupling, facilitating the formation of carbon-carbon bonds, which is crucial in creating complex organic molecules.
  • Material Science: The compound is used in the preparation of functional materials, including sensors and polymers, enhancing properties like conductivity and responsiveness to environmental stimuli.
  • Bioconjugation: It plays a role in bioconjugation chemistry, allowing researchers to attach biomolecules to surfaces or other molecules, which is essential for developing targeted drug delivery systems.
  • Environmental Monitoring: This chemical can be utilized in the detection of pollutants, as it can form complexes with certain environmental contaminants, aiding in the development of sensitive analytical methods.

Citations