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Catalog Number:
40317
CAS Number:
162101-31-7
2-Fluoro-4-methoxyphenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
2-Fluoro-4-methoxybenzeneboronic acid
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Product Information

2-Fluoro-4-methoxyphenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the formation of biaryl compounds, which are crucial in the development of pharmaceuticals and agrochemicals. Its unique fluorine and methoxy substituents enhance its reactivity and selectivity, allowing for more efficient synthesis pathways compared to other boronic acids.

Researchers and industry professionals can leverage 2-Fluoro-4-methoxyphenylboronic acid in the synthesis of complex molecules, including those used in drug discovery and development. Its application extends to the creation of targeted therapies and advanced materials, showcasing its relevance in both academic and industrial settings. The compound's stability and compatibility with various reaction conditions further underscore its utility, making it a preferred choice for chemists seeking reliable and effective reagents in their work.

Synonyms
2-Fluoro-4-methoxybenzeneboronic acid
CAS Number
162101-31-7
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H8BFO3
Molecular Weight
169.95
MDL Number
MFCD04039323
PubChem ID
15789384
Melting Point
109 - 113 °C
Appearance
White to light orange to green powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-Fluoro-4-methoxybenzeneboronic acid
CAS Number
162101-31-7
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H8BFO3
Molecular Weight
169.95
MDL Number
MFCD04039323
PubChem ID
15789384
Melting Point
109 - 113 °C
Appearance
White to light orange to green powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Fluoro-4-methoxyphenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a crucial building block in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and other diseases. Its ability to form stable complexes with biomolecules enhances drug efficacy.
  • Organic Synthesis: It is commonly used in Suzuki-Miyaura cross-coupling reactions, allowing chemists to create complex organic molecules. This application is vital in the production of agrochemicals and fine chemicals.
  • Material Science: The compound is employed in the formulation of advanced materials, such as polymers and coatings, due to its unique properties that improve durability and performance in various applications.
  • Bioconjugation: In biochemistry, it is utilized for labeling biomolecules, facilitating the study of protein interactions and cellular processes, which is essential for research in drug discovery and development.
  • Analytical Chemistry: This boronic acid derivative is used in sensor technology for detecting sugars and other analytes, providing a sensitive and selective method for monitoring biological and environmental samples.

Citations