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Catalog Number:
40314
CAS Number:
157834-21-4
2-Fluoro-3-(trifluoromethyl)phenylboronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
2-Fluoro-3-(trifluoromethyl)benzeneboronic acid
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Product Information

2-Fluoro-3-(trifluoromethyl)phenylboronic acid is a highly versatile compound that plays a significant role in various fields, particularly in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its unique reactivity, making it an essential building block in the development of pharmaceuticals and agrochemicals. Its trifluoromethyl group enhances lipophilicity, which can improve the bioavailability of drug candidates. Researchers utilize this compound in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds that are crucial for constructing complex molecular architectures.

Additionally, 2-Fluoro-3-(trifluoromethyl)phenylboronic acid is valuable in the synthesis of fluorinated compounds, which are increasingly important in the development of new materials and in the field of fluorine chemistry. Its ability to selectively bind to certain substrates allows for targeted modifications in drug design, making it a preferred choice for chemists aiming to optimize therapeutic profiles. With its robust applications and unique properties, this compound is an indispensable tool for researchers and industry professionals looking to innovate in their respective fields.

Synonyms
2-Fluoro-3-(trifluoromethyl)benzeneboronic acid
CAS Number
157834-21-4
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H5BF4O2
Molecular Weight
207.92
MDL Number
MFCD07784336
PubChem ID
16217169
Melting Point
58 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
2-Fluoro-3-(trifluoromethyl)benzeneboronic acid
CAS Number
157834-21-4
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H5BF4O2
Molecular Weight
207.92
MDL Number
MFCD07784336
PubChem ID
16217169
Melting Point
58 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Fluoro-3-(trifluoromethyl)phenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a crucial intermediate in the synthesis of various pharmaceuticals, particularly in developing drugs targeting specific biological pathways.
  • Organic Synthesis: It is employed in cross-coupling reactions, allowing chemists to create complex organic molecules efficiently, which is essential in materials science and agrochemicals.
  • Fluorinated Compound Research: The unique fluorine substituents enhance the stability and reactivity of compounds, making it valuable in studying the properties of fluorinated organic materials.
  • Bioconjugation Techniques: This chemical is used in bioconjugation to attach biomolecules to surfaces or other molecules, facilitating advancements in diagnostics and targeted drug delivery.
  • Material Science: It plays a role in developing new materials with specific electronic or optical properties, contributing to innovations in electronics and nanotechnology.

Citations