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Catalog Number:
40311
CAS Number:
148839-33-2
5-Chloro-2-methylphenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
5-Chloro-2-methylbenzeneboronic acid, 5-Chloro-o-tolylboronic acid
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Product Information

5-Chloro-2-methylphenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. Known for its unique boronic acid functionality, this compound serves as a crucial building block in the development of pharmaceuticals, agrochemicals, and advanced materials. Its ability to form reversible covalent bonds with diols makes it particularly valuable in the synthesis of complex organic molecules, enabling researchers to create targeted compounds with enhanced biological activity.

In the pharmaceutical industry, 5-Chloro-2-methylphenylboronic acid is employed in the development of inhibitors for various enzymes, contributing to advancements in cancer research and treatment. Additionally, its application in cross-coupling reactions, such as Suzuki-Miyaura coupling, allows for the efficient formation of carbon-carbon bonds, facilitating the synthesis of diverse organic compounds. With its favorable reactivity and functional properties, this compound stands out as an essential tool for researchers and industry professionals seeking to innovate and enhance their chemical processes.

Synonyms
5-Chloro-2-methylbenzeneboronic acid, 5-Chloro-o-tolylboronic acid
CAS Number
148839-33-2
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H8BClO2
Molecular Weight
170.4
MDL Number
MFCD03411939
PubChem ID
2773336
Melting Point
186 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5-Chloro-2-methylbenzeneboronic acid, 5-Chloro-o-tolylboronic acid
CAS Number
148839-33-2
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H8BClO2
Molecular Weight
170.4
MDL Number
MFCD03411939
PubChem ID
2773336
Melting Point
186 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Chloro-2-methylphenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, allowing chemists to create complex molecules efficiently.
  • Cross-Coupling Reactions: It plays a crucial role in Suzuki-Miyaura coupling reactions, which are essential for forming carbon-carbon bonds in organic chemistry, particularly in the development of new materials and drugs.
  • Bioconjugation: The boronic acid functional group enables selective binding to diols, making it useful in bioconjugation techniques for labeling biomolecules, which is valuable in diagnostics and therapeutic applications.
  • Sensor Development: This compound is used in the fabrication of sensors that detect glucose levels, benefiting the medical field by providing a means for continuous monitoring of diabetic patients.
  • Material Science: It is utilized in the development of polymeric materials with enhanced properties, such as improved thermal stability and mechanical strength, which are important in various industrial applications.

Citations