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Catalog Number:
40310
CAS Number:
139911-27-6
4-Fluoro-3-methylphenylboronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
4-Fluoro-3-methylbenzeneboronic acid, 4-Fluoro-m-tolylboronic acid
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Product Information

4-Fluoro-3-methylphenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its ability to form stable complexes with diols, making it an essential reagent in Suzuki-Miyaura cross-coupling reactions. Researchers and industry professionals leverage its unique properties to develop pharmaceuticals, agrochemicals, and advanced materials. Its fluorine substitution enhances the compound's electronic properties, allowing for improved reactivity and selectivity in various chemical transformations.

In addition to its applications in synthetic chemistry, 4-Fluoro-3-methylphenylboronic acid is also explored for its potential in drug discovery, particularly in the development of targeted therapies. Its ability to modulate biological pathways makes it a candidate for further research in medicinal applications. With its favorable characteristics and broad applicability, this compound stands out as a valuable tool for chemists seeking to innovate and enhance their research outcomes.

Synonyms
4-Fluoro-3-methylbenzeneboronic acid, 4-Fluoro-m-tolylboronic acid
CAS Number
139911-27-6
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H8BFO2
Molecular Weight
153.95
MDL Number
MFCD01863527
PubChem ID
2774580
Melting Point
217 °C (Lit.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-Fluoro-3-methylbenzeneboronic acid, 4-Fluoro-m-tolylboronic acid
CAS Number
139911-27-6
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H8BFO2
Molecular Weight
153.95
MDL Number
MFCD01863527
PubChem ID
2774580
Melting Point
217 °C (Lit.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Fluoro-3-methylphenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, enabling the development of new drugs and crop protection agents.
  • Catalysis: It is employed in Suzuki-Miyaura cross-coupling reactions, which are essential for forming carbon-carbon bonds in organic chemistry, making it invaluable for researchers in medicinal chemistry.
  • Material Science: The compound is used in the development of advanced materials, including polymers and nanomaterials, which can enhance the properties of coatings and electronic devices.
  • Bioconjugation: It plays a role in bioconjugation techniques, allowing for the attachment of biomolecules to surfaces or other molecules, which is crucial in drug delivery and diagnostic applications.
  • Fluorine Chemistry: The presence of fluorine enhances the biological activity of compounds, making it a valuable tool in the design of new therapeutic agents with improved efficacy and selectivity.

Citations