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Catalog Number:
40309
CAS Number:
137504-86-0
4-Chloro-3-fluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
4-Chloro-3-fluorobenzeneboronic acid
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Product Information

4-Chloro-3-fluorophenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the development of complex organic molecules, including pharmaceuticals and agrochemicals. Its unique combination of chlorine and fluorine substituents enhances its reactivity and selectivity, allowing researchers to create compounds with specific properties tailored to their applications.

In addition to its role in synthetic chemistry, 4-Chloro-3-fluorophenylboronic acid has shown potential in the development of targeted therapies, particularly in the field of cancer research. Its ability to form stable complexes with various substrates makes it a valuable tool for drug discovery and development. Researchers can leverage its properties to explore new therapeutic avenues, making it an indispensable asset in both academic and industrial laboratories.

Synonyms
4-Chloro-3-fluorobenzeneboronic acid
CAS Number
137504-86-0
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD01319010
PubChem ID
2778656
Melting Point
144 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-Chloro-3-fluorobenzeneboronic acid
CAS Number
137504-86-0
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD01319010
PubChem ID
2778656
Melting Point
144 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Chloro-3-fluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound plays a crucial role in the synthesis of various pharmaceuticals, particularly in the creation of targeted therapies for cancer treatment.
  • Organic Synthesis: It serves as a versatile building block in organic chemistry, enabling the formation of complex molecules through cross-coupling reactions, which are essential in creating new materials.
  • Bioconjugation: The compound is used to attach biomolecules in bioconjugation processes, enhancing drug delivery systems and improving the efficacy of therapeutic agents.
  • Sensor Technology: It is applied in the development of chemical sensors, particularly for detecting specific ions or molecules, which is valuable in environmental monitoring and safety applications.
  • Research in Material Science: This boronic acid derivative is utilized in the development of advanced materials, including polymers and nanomaterials, which have applications in electronics and nanotechnology.

Citations