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Catalog Number:
40302
CAS Number:
182344-16-7
4-Fluoro-2-(trifluoromethyl)phenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
4-Fluoro-2-(trifluoromethyl)benzeneboronic acid
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Product Information

4-Fluoro-2-(trifluoromethyl)phenylboronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its unique trifluoromethyl group, which enhances its reactivity and selectivity in cross-coupling reactions, particularly in the formation of carbon-carbon bonds. Its ability to act as a key building block in the synthesis of complex molecules makes it invaluable in the development of pharmaceuticals and agrochemicals. Researchers utilize this compound in the synthesis of biologically active compounds, including potential drug candidates, due to its favorable electronic properties and stability under various reaction conditions.

In addition to its applications in organic synthesis, 4-Fluoro-2-(trifluoromethyl)phenylboronic acid is also employed in materials science for the development of advanced materials and polymers. Its unique properties allow for the fine-tuning of material characteristics, making it suitable for applications in electronics and nanotechnology. With its broad range of applications, this compound stands out as a vital tool for researchers and industry professionals seeking to innovate and enhance their projects.

Synonyms
4-Fluoro-2-(trifluoromethyl)benzeneboronic acid
CAS Number
182344-16-7
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H5BF4O2
Molecular Weight
207.92
MDL Number
MFCD08062379
PubChem ID
12109469
Melting Point
186 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8°C
General Information
Synonyms
4-Fluoro-2-(trifluoromethyl)benzeneboronic acid
CAS Number
182344-16-7
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H5BF4O2
Molecular Weight
207.92
MDL Number
MFCD08062379
PubChem ID
12109469
Melting Point
186 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Fluoro-2-(trifluoromethyl)phenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a crucial building block in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and other diseases.
  • Organic Synthesis: It is used in cross-coupling reactions, such as Suzuki-Miyaura coupling, enabling the formation of carbon-carbon bonds, which are essential in creating complex organic molecules.
  • Material Science: The compound is applied in the development of advanced materials, including polymers and nanomaterials, enhancing properties like thermal stability and conductivity.
  • Fluorine Chemistry: Its unique trifluoromethyl group makes it valuable in fluorine chemistry, allowing researchers to introduce fluorine into organic compounds, which can improve biological activity and stability.
  • Analytical Chemistry: This boronic acid is utilized in sensor technology, particularly in the detection of sugars and other biomolecules, offering high sensitivity and selectivity in analytical applications.

Citations