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Catalog Number:
40300
CAS Number:
163517-61-1
3-Fluoro-2-methylphenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
3-Fluoro-2-methylbenzeneboronic acid, 3-Fluoro-o-tolylboronic acid
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Product Information

3-Fluoro-2-methylphenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its ability to form stable complexes with diols, making it an essential reagent in Suzuki-Miyaura cross-coupling reactions. Researchers and industry professionals leverage its unique properties to synthesize a variety of complex organic molecules, including pharmaceuticals and agrochemicals. Its fluorine substitution enhances the compound's reactivity and selectivity, providing significant advantages in the development of targeted therapies and innovative materials.

In addition to its role in synthetic chemistry, 3-Fluoro-2-methylphenylboronic acid is also employed in the development of sensors and catalysts, showcasing its broad applicability across multiple fields. Its compatibility with various reaction conditions and substrates allows for greater flexibility in experimental design, making it a preferred choice for researchers aiming to optimize reaction yields and efficiencies. With its robust performance and diverse applications, this compound stands out as a valuable tool for advancing chemical research and industrial processes.

Synonyms
3-Fluoro-2-methylbenzeneboronic acid, 3-Fluoro-o-tolylboronic acid
CAS Number
163517-61-1
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H8BFO2
Molecular Weight
153.95
MDL Number
MFCD07368679
PubChem ID
2783191
Melting Point
144 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
3-Fluoro-2-methylbenzeneboronic acid, 3-Fluoro-o-tolylboronic acid
CAS Number
163517-61-1
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H8BFO2
Molecular Weight
153.95
MDL Number
MFCD07368679
PubChem ID
2783191
Melting Point
144 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-Fluoro-2-methylphenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound is crucial in the synthesis of various pharmaceuticals, particularly in the development of targeted therapies for cancer. Its ability to form stable complexes with biomolecules enhances drug efficacy.
  • Organic Synthesis: It serves as a versatile building block in organic chemistry, allowing researchers to create complex molecules through cross-coupling reactions. This is particularly beneficial in the production of fine chemicals and agrochemicals.
  • Materials Science: The compound is used in the development of advanced materials, including polymers and nanomaterials, which have applications in electronics and coatings, providing improved durability and performance.
  • Bioconjugation: Its boronic acid functionality allows for selective binding to diols, making it useful in bioconjugation techniques for labeling biomolecules, which is essential in diagnostics and therapeutic applications.
  • Environmental Chemistry: This compound can be employed in the detection and removal of pollutants, particularly in water treatment processes, due to its reactivity with specific contaminants, thus contributing to environmental sustainability.

Citations