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Catalog Number:
40299
CAS Number:
313545-32-3
2-Chloro-6-fluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
2-Chloro-6-fluorobenzeneboronic acid
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Product Information

2-Chloro-6-fluorophenylboronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it invaluable for the formation of carbon-carbon bonds. Researchers and industry professionals utilize this compound in the development of pharmaceuticals, agrochemicals, and advanced materials. Its unique structure allows for selective functionalization, which is essential in the design of complex molecules.

In addition to its synthetic applications, 2-Chloro-6-fluorophenylboronic acid has shown promise in the field of biochemistry, particularly in the development of targeted therapies. Its ability to form stable complexes with various substrates enhances its utility in drug discovery and development. The compound's favorable reactivity profile and compatibility with a wide range of functional groups make it a preferred choice for chemists looking to streamline their synthetic pathways.

Synonyms
2-Chloro-6-fluorobenzeneboronic acid
CAS Number
313545-32-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD04039892
PubChem ID
3549395
Melting Point
135 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
2-Chloro-6-fluorobenzeneboronic acid
CAS Number
313545-32-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD04039892
PubChem ID
3549395
Melting Point
135 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Chloro-6-fluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a crucial building block in the synthesis of various pharmaceuticals, particularly in the development of targeted therapies for cancer and other diseases.
  • Organic Synthesis: It is employed in cross-coupling reactions, such as Suzuki-Miyaura coupling, which allows for the formation of carbon-carbon bonds, essential in creating complex organic molecules.
  • Material Science: The compound is used in the development of advanced materials, including polymers and nanomaterials, enhancing properties like conductivity and strength.
  • Diagnostics: It plays a role in the design of diagnostic agents, particularly in imaging techniques that help in the early detection of diseases.
  • Research in Agrochemicals: This chemical is explored for its potential in developing new agrochemical products, improving crop protection and yield.

Citations