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Catalog Number:
40298
CAS Number:
193353-35-4
2-Chloro-5-methylphenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
2-Chloro-5-methylbenzeneboronic acid, 6-Chloro-m-tolylboronic acid
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$154.93 /1G
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Product Information

2-Chloro-5-methylphenylboronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Its unique structure allows for selective functionalization, which is particularly valuable in the development of targeted therapies and advanced materials. Researchers appreciate its stability and reactivity, which facilitate the formation of carbon-carbon bonds, essential for creating diverse chemical architectures.

In addition to its applications in organic synthesis, 2-Chloro-5-methylphenylboronic acid is also employed in the development of sensors and catalysts. Its boronic acid functionality enables it to interact with diols, making it useful in the design of glucose sensors for diabetes management. The compound's compatibility with various reaction conditions enhances its utility in both academic research and industrial applications, providing a reliable option for chemists seeking efficient and effective synthetic pathways.

Synonyms
2-Chloro-5-methylbenzeneboronic acid, 6-Chloro-m-tolylboronic acid
CAS Number
193353-35-4
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H8BClO2
Molecular Weight
170.4
MDL Number
MFCD06659822
PubChem ID
17750235
Melting Point
205 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
2-Chloro-5-methylbenzeneboronic acid, 6-Chloro-m-tolylboronic acid
CAS Number
193353-35-4
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H8BClO2
Molecular Weight
170.4
MDL Number
MFCD06659822
PubChem ID
17750235
Melting Point
205 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Chloro-5-methylphenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a key reagent in Suzuki-Miyaura cross-coupling reactions, allowing chemists to create complex organic molecules efficiently, which is crucial in pharmaceutical development.
  • Drug Development: Its ability to form stable complexes with various biomolecules makes it valuable in designing new drugs, particularly in targeting specific enzymes or receptors in disease treatment.
  • Material Science: Used in the synthesis of boron-containing polymers and materials, it enhances properties such as thermal stability and mechanical strength, which are important in creating advanced materials for electronics.
  • Bioconjugation: The compound can be employed in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in developing biosensors and diagnostic tools.
  • Environmental Chemistry: It plays a role in the development of sensors for detecting pollutants, helping industries monitor and reduce their environmental impact effectively.

Citations