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Catalog Number:
40295
CAS Number:
279261-81-3
3-Chloro-4-ethoxyphenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
3-Chloro-4-ethoxybenzeneboronic acid
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Product Information

3-Chloro-4-ethoxyphenylboronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its ability to form stable complexes with diols, making it an essential reagent in Suzuki-Miyaura cross-coupling reactions. Its unique structure, featuring a chloro and ethoxy group, enhances its reactivity and selectivity, allowing for the efficient synthesis of complex organic molecules. Researchers and industry professionals utilize this compound in the development of pharmaceuticals, agrochemicals, and advanced materials, where precision and efficiency are paramount.

The practical applications of 3-Chloro-4-ethoxyphenylboronic acid extend to the synthesis of biologically active compounds, including potential drug candidates. Its effectiveness in facilitating carbon-carbon bond formation makes it an invaluable tool in the creation of intricate molecular architectures. Additionally, its compatibility with various reaction conditions allows for flexibility in laboratory settings, catering to diverse synthetic needs. With its proven track record in enhancing reaction yields and selectivity, this compound stands out as a preferred choice for chemists aiming to streamline their synthetic processes.

Synonyms
3-Chloro-4-ethoxybenzeneboronic acid
CAS Number
279261-81-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C8H10BClO3
Molecular Weight
200.43
MDL Number
MFCD03701556
PubChem ID
3717658
Melting Point
239 °C (Lit.)
Appearance
White to slightly yellow crystalline powd
Conditions
Store at RT
General Information
Synonyms
3-Chloro-4-ethoxybenzeneboronic acid
CAS Number
279261-81-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C8H10BClO3
Molecular Weight
200.43
MDL Number
MFCD03701556
PubChem ID
3717658
Melting Point
239 °C (Lit.)
Appearance
White to slightly yellow crystalline powd
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-Chloro-4-ethoxyphenylboronic acid is widely utilized in research focused on:

  • Drug Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-cancer agents. Its ability to form stable complexes with biomolecules enhances drug efficacy.
  • Organic Synthesis: It is employed in cross-coupling reactions, such as Suzuki-Miyaura coupling, which is essential for creating complex organic molecules. This application is crucial in the production of agrochemicals and fine chemicals.
  • Material Science: The compound is used in the fabrication of advanced materials, including polymers and nanomaterials, which are essential for electronics and renewable energy technologies.
  • Bioconjugation: It plays a role in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is vital in developing biosensors and diagnostic tools.
  • Research in Catalysis: This chemical is significant in catalysis research, where it aids in the development of new catalytic systems that can enhance reaction efficiency and selectivity in various chemical processes.

Citations