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Catalog Number:
40288
CAS Number:
170981-26-7
2-Fluoro-4-methylphenylboronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
2-Fluoro-4-methylbenzeneboronic acid
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Product Information

2-Fluoro-4-methylphenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block in the development of pharmaceuticals and agrochemicals. Its unique fluorine substituent enhances its reactivity and selectivity, allowing for the efficient formation of carbon-carbon bonds. Researchers appreciate its role in synthesizing complex molecules, including biologically active compounds and advanced materials.

In addition to its synthetic applications, 2-Fluoro-4-methylphenylboronic acid has shown promise in the development of targeted therapies, particularly in the field of cancer research. Its ability to form stable complexes with various substrates makes it an attractive candidate for drug discovery and development. With its favorable properties and practical applications, this compound stands out as a valuable resource for chemists and industry professionals seeking innovative solutions in their research and product development efforts.

Synonyms
2-Fluoro-4-methylbenzeneboronic acid
CAS Number
170981-26-7
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H8BFO2
Molecular Weight
153.95
MDL Number
MFCD05664239
PubChem ID
2783132
Melting Point
230 °C (Lit.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
2-Fluoro-4-methylbenzeneboronic acid
CAS Number
170981-26-7
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H8BFO2
Molecular Weight
153.95
MDL Number
MFCD05664239
PubChem ID
2783132
Melting Point
230 °C (Lit.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Fluoro-4-methylphenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound is crucial in synthesizing various pharmaceuticals, particularly in the development of targeted cancer therapies, due to its ability to form stable complexes with biomolecules.
  • Organic Synthesis: It serves as a versatile building block in organic synthesis, allowing chemists to create complex molecules efficiently, which is essential in the production of agrochemicals and fine chemicals.
  • Materials Science: The compound is used in the development of advanced materials, including polymers and nanomaterials, enhancing properties like strength and thermal stability.
  • Bioconjugation: It plays a significant role in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other compounds, which is vital in diagnostics and therapeutic applications.
  • Analytical Chemistry: This boronic acid is employed in analytical methods for detecting and quantifying sugars and other biomolecules, providing a reliable tool for researchers in biochemistry and food science.

Citations