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Catalog Number:
40286
CAS Number:
481681-02-1
4-Fluoro-3-(hydroxymethyl)phenylboronic acid
Purity:
≥ 97% (HPLC)
Synonym(s):
4-Fluoro-3-(hydroxymethyl)benzeneboronic acid
Documents
$83.42 /200MG
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Product Information

4-Fluoro-3-(hydroxymethyl)phenylboronic acid is a versatile compound that plays a significant role in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its unique ability to form reversible covalent bonds with diols, making it an essential reagent in the development of various pharmaceuticals and agrochemicals. Its applications extend to the synthesis of complex molecules, where it serves as a crucial building block in the preparation of biologically active compounds. Researchers have leveraged its properties in the design of targeted therapies, particularly in the field of cancer research, where it aids in the development of inhibitors that can selectively disrupt tumor growth.

Additionally, 4-Fluoro-3-(hydroxymethyl)phenylboronic acid is valued for its stability and ease of handling, which enhances its usability in laboratory settings. Its fluorinated structure provides unique electronic properties that can improve the efficacy of drug candidates. This compound is particularly advantageous for researchers looking to optimize lead compounds due to its ability to facilitate the formation of boronate esters, which are pivotal in various coupling reactions. With its broad range of applications and benefits, this compound is a valuable asset for professionals in pharmaceuticals and chemical research.

Synonyms
4-Fluoro-3-(hydroxymethyl)benzeneboronic acid
CAS Number
481681-02-1
Purity
≥ 97% (HPLC)
Molecular Formula
C7H8BFO3
Molecular Weight
169.95
MDL Number
MFCD08235075
PubChem ID
21865588
Melting Point
126 °C (Lit.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-Fluoro-3-(hydroxymethyl)benzeneboronic acid
CAS Number
481681-02-1
Purity
≥ 97% (HPLC)
Molecular Formula
C7H8BFO3
Molecular Weight
169.95
MDL Number
MFCD08235075
PubChem ID
21865588
Melting Point
126 °C (Lit.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Fluoro-3-(hydroxymethyl)phenylboronic acid is widely utilized in research focused on:

  • Drug Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and other diseases.
  • Bioconjugation: It is used in bioconjugation processes to attach biomolecules to surfaces or other compounds, enhancing the functionality of diagnostic tools and therapeutic agents.
  • Organic Synthesis: This chemical plays a crucial role in organic synthesis, particularly in the formation of carbon-boron bonds, which are essential in creating complex organic molecules.
  • Material Science: It is applied in the development of advanced materials, such as polymers and coatings, that require specific chemical properties for improved performance.
  • Analytical Chemistry: The compound is utilized in analytical methods for detecting and quantifying phenolic compounds in various samples, aiding in environmental monitoring and quality control.

Citations