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Catalog Number:
40284
CAS Number:
160591-91-3
4-Chloro-2-fluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
4-Chloro-2-fluorobenzeneboronic acid
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Product Information

4-Chloro-2-fluorophenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its ability to form stable complexes with diols, making it an essential reagent in Suzuki-Miyaura cross-coupling reactions. Its unique structure, featuring both chlorine and fluorine substituents, enhances its reactivity and selectivity, allowing for the efficient synthesis of complex organic molecules. Researchers appreciate its role in developing pharmaceuticals, agrochemicals, and advanced materials, where precision and specificity are paramount.

In addition to its synthetic applications, 4-Chloro-2-fluorophenylboronic acid serves as a valuable tool in the study of biological systems, particularly in the development of targeted therapies. Its ability to modulate biological pathways makes it a candidate for further exploration in drug discovery. With its favorable properties and broad applicability, this compound stands out as a key ingredient for professionals seeking reliable and effective solutions in their research and development endeavors.

Synonyms
4-Chloro-2-fluorobenzeneboronic acid
CAS Number
160591-91-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD02684293
PubChem ID
4193595
Melting Point
250 °C (Lit.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-Chloro-2-fluorobenzeneboronic acid
CAS Number
160591-91-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD02684293
PubChem ID
4193595
Melting Point
250 °C (Lit.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Chloro-2-fluorophenylboronic acid is widely utilized in research focused on

  • Pharmaceutical Development: This compound is crucial in the synthesis of various pharmaceuticals, particularly in the development of targeted cancer therapies. Its ability to form stable complexes with biomolecules enhances drug efficacy.
  • Organic Synthesis: It serves as a key reagent in Suzuki coupling reactions, allowing chemists to create complex organic molecules efficiently. This is particularly valuable in the production of agrochemicals and fine chemicals.
  • Material Science: The compound is used in the development of advanced materials, including polymers and nanomaterials, which can be tailored for specific applications such as sensors or drug delivery systems.
  • Bioconjugation: Its boronic acid functionality enables the selective labeling of biomolecules, facilitating studies in biochemistry and molecular biology, particularly in tracking cellular processes.
  • Environmental Chemistry: This chemical can be applied in the detection and removal of pollutants, leveraging its reactivity to bind with harmful substances, thus aiding in environmental remediation efforts.

Citations