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Catalog Number:
40280
CAS Number:
159020-59-4
3-Fluoro-5-(trifluoromethyl)phenylboronic acid
Purity:
98 - 105% (Assay by titration)
Synonym(s):
3-Fluoro-5-(trifluoromethyl)benzeneboronic acid
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Product Information

3-Fluoro-5-(trifluoromethyl)phenylboronic acid is a highly versatile compound that plays a significant role in the field of organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the synthesis of complex organic molecules. Its unique trifluoromethyl group enhances the compound's lipophilicity and biological activity, which is advantageous in the development of pharmaceuticals and agrochemicals. Researchers and industry professionals utilize this compound to create various functionalized compounds, including potential drug candidates and advanced materials.

Additionally, 3-Fluoro-5-(trifluoromethyl)phenylboronic acid exhibits excellent stability and reactivity under a range of conditions, making it suitable for diverse applications in both laboratory and industrial settings. Its ability to form stable complexes with various substrates allows for the development of innovative solutions in drug discovery and material science. With its unique properties and practical applications, this compound is an invaluable asset for those engaged in cutting-edge research and development.

Synonyms
3-Fluoro-5-(trifluoromethyl)benzeneboronic acid
CAS Number
159020-59-4
Purity
98 - 105% (Assay by titration)
Molecular Formula
C7H5BF4O2
Molecular Weight
207.92
MDL Number
MFCD06657735
PubChem ID
2783192
Melting Point
168 °C (Lit.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
3-Fluoro-5-(trifluoromethyl)benzeneboronic acid
CAS Number
159020-59-4
Purity
98 - 105% (Assay by titration)
Molecular Formula
C7H5BF4O2
Molecular Weight
207.92
MDL Number
MFCD06657735
PubChem ID
2783192
Melting Point
168 °C (Lit.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-Fluoro-5-(trifluoromethyl)phenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound plays a crucial role in the synthesis of various pharmaceuticals, particularly in creating targeted therapies for cancer treatment, due to its ability to form stable complexes with biological targets.
  • Organic Synthesis: It is a valuable reagent in organic chemistry for cross-coupling reactions, enabling the formation of carbon-carbon bonds, which is essential in the production of complex organic molecules.
  • Material Science: The compound is used in developing advanced materials, including polymers and coatings, that require specific electronic or optical properties, enhancing performance in various applications.
  • Fluorinated Compounds: Its unique fluorine substituents make it a key building block in synthesizing fluorinated compounds, which are important in agrochemicals and specialty chemicals, providing enhanced stability and reactivity.
  • Analytical Chemistry: This boronic acid derivative is employed in analytical methods for detecting and quantifying sugars and other biomolecules, offering high sensitivity and specificity in various assays.

Citations