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Catalog Number:
40278
CAS Number:
503309-11-3
2-Fluoro-4-(trifluoromethyl)phenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
2-Fluoro-4-(trifluoromethyl)benzeneboronic acid
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Product Information

2-Fluoro-4-(trifluoromethyl)phenylboronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is characterized by its unique trifluoromethyl and fluorine substituents, which enhance its reactivity and selectivity in various chemical reactions. It is particularly valuable in the development of pharmaceuticals, agrochemicals, and advanced materials. Researchers utilize this compound in Suzuki coupling reactions, enabling the formation of carbon-carbon bonds that are essential for constructing complex organic molecules. Its ability to act as a building block in the synthesis of biologically active compounds makes it a preferred choice for chemists aiming to create innovative solutions in drug discovery and development.

Additionally, 2-Fluoro-4-(trifluoromethyl)phenylboronic acid offers notable advantages over similar compounds, such as improved solubility and stability in various solvents, which can lead to more efficient reactions and higher yields. Its unique properties make it an essential tool for researchers and industry professionals looking to enhance their synthetic strategies and achieve more effective results in their projects.

Synonyms
2-Fluoro-4-(trifluoromethyl)benzeneboronic acid
CAS Number
503309-11-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H5BF4O2
Molecular Weight
207.92
MDL Number
MFCD03094995
PubChem ID
16414145
Melting Point
116 °C (Lit.)
Density
1.44 g/mL
Appearance
White to slightly yellow crystalline powder
Boiling Point
251.91 °C (Lit.)
Refractive Index
n20D = 1.44
Conditions
Store at RT
General Information
Synonyms
2-Fluoro-4-(trifluoromethyl)benzeneboronic acid
CAS Number
503309-11-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H5BF4O2
Molecular Weight
207.92
MDL Number
MFCD03094995
PubChem ID
16414145
Melting Point
116 °C (Lit.)
Density
1.44 g/mL
Appearance
White to slightly yellow crystalline powder
Boiling Point
251.91 °C (Lit.)
Refractive Index
n20D = 1.44
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Fluoro-4-(trifluoromethyl)phenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound plays a crucial role in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting specific biological pathways.
  • Organic Synthesis: It serves as a versatile building block in organic chemistry, enabling the creation of complex molecules through cross-coupling reactions, which are essential in producing agrochemicals and fine chemicals.
  • Material Science: The compound is used in the formulation of advanced materials, including polymers and coatings, enhancing their properties such as durability and resistance to environmental factors.
  • Fluorine Chemistry: Its unique fluorinated structure makes it valuable in fluorine chemistry, allowing researchers to explore new pathways for creating fluorinated compounds with improved performance in various applications.
  • Analytical Chemistry: This chemical is utilized in analytical methods for detecting and quantifying specific compounds, providing accurate results that are crucial for quality control in various industries.

Citations