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Catalog Number:
40277
CAS Number:
259209-20-6
5-Fluoro-2-hydroxyphenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
5-Fluoro-2-hydroxybenzeneboronic acid
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Product Information

5-Fluoro-2-hydroxyphenylboronic acid is a versatile compound widely utilized in pharmaceutical research and organic synthesis. This boronic acid derivative is recognized for its ability to form stable complexes with diols, making it an essential reagent in the development of various biologically active molecules. Its unique fluorine substitution enhances its reactivity and selectivity in cross-coupling reactions, particularly in the synthesis of complex organic compounds. Researchers have leveraged this compound in the design of targeted therapies, especially in oncology, where it aids in the development of novel anti-cancer agents.

In addition to its applications in medicinal chemistry, 5-Fluoro-2-hydroxyphenylboronic acid is also valuable in materials science, where it contributes to the creation of advanced materials with tailored properties. The compound's ability to participate in Suzuki-Miyaura coupling reactions makes it a key player in the synthesis of functionalized polymers and organic electronics. With its broad range of applications and significant advantages over similar compounds, this boronic acid is an indispensable tool for researchers and industry professionals aiming to innovate and enhance their projects.

Synonyms
5-Fluoro-2-hydroxybenzeneboronic acid
CAS Number
259209-20-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H6BFO3
Molecular Weight
155.92
MDL Number
MFCD03095357
PubChem ID
3772476
Melting Point
166 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5-Fluoro-2-hydroxybenzeneboronic acid
CAS Number
259209-20-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H6BFO3
Molecular Weight
155.92
MDL Number
MFCD03095357
PubChem ID
3772476
Melting Point
166 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Fluoro-2-hydroxyphenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound plays a crucial role in the synthesis of various pharmaceuticals, particularly in developing drugs targeting cancer and other diseases. Its ability to form stable complexes with biomolecules enhances drug efficacy.
  • Bioconjugation: It is used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other compounds. This is particularly beneficial in creating targeted drug delivery systems.
  • Organic Synthesis: The compound serves as a versatile building block in organic synthesis, facilitating the creation of complex organic molecules. This application is vital in the production of agrochemicals and specialty chemicals.
  • Analytical Chemistry: In analytical applications, it is employed as a reagent for detecting and quantifying phenolic compounds in various samples, which is essential in environmental monitoring and food safety testing.
  • Material Science: The compound is also explored in material science for developing new materials with specific properties, such as enhanced conductivity or improved mechanical strength, which can be applied in electronics and nanotechnology.

Citations