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Catalog Number:
40276
CAS Number:
352535-82-1
3-Chloro-2-fluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
3-Chloro-2-fluorobenzeneboronic acid
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Product Information

3-Chloro-2-fluorophenylboronic acid is a versatile boronic acid derivative, recognized for its significant role in organic synthesis and medicinal chemistry. This compound features a unique combination of a chloro and a fluoro substituent on the phenyl ring, enhancing its reactivity and selectivity in various chemical reactions. It is particularly valuable in Suzuki coupling reactions, which are essential for forming carbon-carbon bonds in the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Researchers appreciate its utility in developing novel compounds with potential therapeutic applications, especially in the fields of oncology and infectious diseases.

The compound's ability to act as a building block in the synthesis of biologically active molecules makes it a preferred choice among chemists. Its stability and compatibility with various reaction conditions further enhance its appeal, allowing for streamlined processes in laboratory settings. With its growing importance in the development of targeted therapies and advanced materials, 3-Chloro-2-fluorophenylboronic acid stands out as a crucial reagent for professionals seeking to innovate in chemical research and development.

Synonyms
3-Chloro-2-fluorobenzeneboronic acid
CAS Number
352535-82-1
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD05664224
PubChem ID
16217158
Melting Point
247 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
3-Chloro-2-fluorobenzeneboronic acid
CAS Number
352535-82-1
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD05664224
PubChem ID
16217158
Melting Point
247 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-Chloro-2-fluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound is essential in the synthesis of various pharmaceuticals, particularly in creating new drug candidates that target specific diseases, enhancing therapeutic efficacy.
  • Organic Synthesis: It serves as a versatile building block in organic chemistry, allowing chemists to construct complex molecules through Suzuki coupling reactions, which are crucial for developing new materials.
  • Bioconjugation: The compound is used in bioconjugation processes to attach biomolecules to surfaces or other molecules, facilitating advancements in targeted drug delivery systems and diagnostics.
  • Material Science: It plays a role in the development of advanced materials, such as polymers and nanomaterials, which are utilized in electronics and coatings, improving performance and durability.
  • Research in Agrochemicals: This chemical is also explored for its potential applications in agrochemicals, contributing to the development of new pesticides or herbicides that are more effective and environmentally friendly.

Citations