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Catalog Number:
40274
CAS Number:
182344-23-6
4-Fluoro-3-(trifluoromethyl)phenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
4-Fluoro-3-(trifluoromethyl)benzeneboronic acid
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Product Information

4-Fluoro-3-(trifluoromethyl)phenylboronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its unique ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the development of complex organic molecules, including pharmaceuticals and agrochemicals. Its trifluoromethyl group enhances lipophilicity and bioactivity, which is particularly beneficial in drug design, allowing for the creation of compounds with improved efficacy and selectivity.

Researchers and industry professionals can leverage 4-Fluoro-3-(trifluoromethyl)phenylboronic acid in various applications, such as the synthesis of fluorinated compounds, which are increasingly important in the development of new therapeutic agents. Its stability and reactivity under mild conditions make it an attractive choice for both academic research and industrial applications. By incorporating this compound into their workflows, chemists can streamline the synthesis of target molecules, ultimately accelerating the discovery and development of innovative solutions in pharmaceuticals and materials science.

Synonyms
4-Fluoro-3-(trifluoromethyl)benzeneboronic acid
CAS Number
182344-23-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H5BF4O2
Molecular Weight
207.92
MDL Number
MFCD07363787
PubChem ID
17750051
Melting Point
174 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-Fluoro-3-(trifluoromethyl)benzeneboronic acid
CAS Number
182344-23-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H5BF4O2
Molecular Weight
207.92
MDL Number
MFCD07363787
PubChem ID
17750051
Melting Point
174 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Fluoro-3-(trifluoromethyl)phenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound plays a crucial role in the synthesis of various pharmaceuticals, particularly in creating compounds that target specific biological pathways, enhancing drug efficacy.
  • Organic Synthesis: It serves as a versatile building block in organic chemistry, allowing researchers to create complex molecules with precision, which is essential for developing new materials and chemicals.
  • Materials Science: The compound is used in the production of advanced materials, including polymers and coatings, which benefit from its unique chemical properties, leading to improved durability and performance.
  • Fluorinated Compounds: It is instrumental in the preparation of fluorinated compounds, which are valuable in various applications, including agrochemicals and specialty chemicals, due to their enhanced stability and reactivity.
  • Analytical Chemistry: This boronic acid derivative is utilized in analytical methods for detecting and quantifying specific biomolecules, proving essential in fields like biochemistry and environmental science.

Citations