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Catalog Number:
40273
CAS Number:
163517-62-2
5-Fluoro-2-methylphenylboronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
5-Fluoro-2-methylbenzeneboronic acid
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Product Information

5-Fluoro-2-methylphenylboronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its ability to form stable complexes with diols, making it an essential reagent in Suzuki-Miyaura cross-coupling reactions. Its unique fluorine substitution enhances its reactivity and selectivity, allowing for the efficient synthesis of complex organic molecules. Researchers and industry professionals utilize this compound in the development of pharmaceuticals, agrochemicals, and advanced materials, particularly in the creation of biologically active compounds and functionalized polymers.

The practical applications of 5-Fluoro-2-methylphenylboronic acid extend to the synthesis of key intermediates in drug discovery, where its ability to facilitate carbon-carbon bond formation is invaluable. Additionally, its compatibility with various functional groups makes it a preferred choice for chemists looking to streamline their synthetic pathways. With its distinctive properties and broad applicability, this compound stands out as a valuable tool for enhancing research and development efforts in diverse chemical fields.

Synonyms
5-Fluoro-2-methylbenzeneboronic acid
CAS Number
163517-62-2
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H8BFO2
Molecular Weight
153.95
MDL Number
MFCD03095047
PubChem ID
2783190
Melting Point
148 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
5-Fluoro-2-methylbenzeneboronic acid
CAS Number
163517-62-2
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H8BFO2
Molecular Weight
153.95
MDL Number
MFCD03095047
PubChem ID
2783190
Melting Point
148 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Fluoro-2-methylphenylboronic acid is widely utilized in research focused on:

  • Drug Development: This compound serves as a key building block in the synthesis of various pharmaceuticals, particularly in the development of anti-cancer agents. Its ability to form stable complexes with biomolecules enhances drug efficacy.
  • Organic Synthesis: It is employed in Suzuki-Miyaura cross-coupling reactions, which are crucial for creating complex organic molecules. This application is vital in the production of agrochemicals and fine chemicals.
  • Material Science: The compound is used in creating advanced materials, such as polymers and nanomaterials, which have applications in electronics and coatings, providing improved durability and performance.
  • Bioconjugation: Its boronic acid functionality allows for selective binding to diols, making it useful in bioconjugation techniques. This is particularly beneficial in the development of targeted drug delivery systems.
  • Analytical Chemistry: It is utilized in sensor technology for detecting glucose levels, offering a more efficient and sensitive method compared to traditional glucose sensors, which is essential for diabetes management.

Citations