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Catalog Number:
40268
CAS Number:
161950-10-3
4-Chloro-3-methylphenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
4-Chloro-3-methylbenzeneboronic acid, 4-Chloro-m-tolylboronic acid
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Product Information

4-Chloro-3-methylphenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valuable for its ability to form stable complexes with diols, making it an essential reagent in Suzuki-Miyaura cross-coupling reactions. Researchers and industry professionals leverage its unique properties to synthesize complex organic molecules, including pharmaceuticals and agrochemicals. Its application extends to the development of advanced materials and sensors, where its reactivity with various substrates can be harnessed for innovative solutions.

The compound's distinct chloromethyl and boronic acid functional groups enhance its reactivity and selectivity in chemical transformations, providing a significant advantage over similar compounds. This makes 4-Chloro-3-methylphenylboronic acid an ideal choice for those looking to streamline their synthetic pathways while achieving high yields and purity. Whether in academic research or industrial applications, this compound stands out for its reliability and effectiveness in facilitating complex chemical reactions.

Synonyms
4-Chloro-3-methylbenzeneboronic acid, 4-Chloro-m-tolylboronic acid
CAS Number
161950-10-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H8BClO2
Molecular Weight
170.4
MDL Number
MFCD02683104
PubChem ID
3786632
Melting Point
258 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-Chloro-3-methylbenzeneboronic acid, 4-Chloro-m-tolylboronic acid
CAS Number
161950-10-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H8BClO2
Molecular Weight
170.4
MDL Number
MFCD02683104
PubChem ID
3786632
Melting Point
258 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Chloro-3-methylphenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a key building block in the synthesis of various organic molecules, particularly in the development of pharmaceuticals and agrochemicals.
  • Cross-Coupling Reactions: It is commonly employed in Suzuki-Miyaura coupling reactions, which are essential for forming carbon-carbon bonds in complex organic compounds.
  • Material Science: The compound is used in the development of advanced materials, including polymers and nanomaterials, enhancing properties like conductivity and strength.
  • Bioconjugation: It plays a role in bioconjugation chemistry, allowing for the attachment of biomolecules to surfaces or other molecules, which is crucial in drug delivery systems.
  • Analytical Chemistry: This chemical is utilized in the preparation of sensors and probes for detecting various analytes, providing precise measurements in environmental and biological samples.

Citations