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Catalog Number:
40266
CAS Number:
121219-16-7
2,3-Difluorophenylboronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
2,3-Difluorobenzeneboronic acid
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Product Information

2,3-Difluorophenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its ability to form stable complexes with diols, making it an essential reagent in Suzuki-Miyaura cross-coupling reactions. Its unique fluorine substituents enhance its reactivity and selectivity, allowing for the development of complex molecular architectures. Researchers have leveraged 2,3-Difluorophenylboronic acid in the synthesis of pharmaceuticals, agrochemicals, and materials science applications, showcasing its importance in advancing chemical research and product development.

The compound's properties, including its solubility in common organic solvents and its compatibility with various functional groups, make it an attractive choice for chemists seeking efficient pathways in synthetic methodologies. Additionally, its role in the preparation of fluorinated compounds is particularly valuable in the pharmaceutical industry, where fluorine atoms can significantly influence the biological activity of drug candidates. With its proven track record in enhancing reaction outcomes, 2,3-Difluorophenylboronic acid stands out as a key player in modern synthetic chemistry.

Synonyms
2,3-Difluorobenzeneboronic acid
CAS Number
121219-16-7
Purity
95 - 105% (Assay by titration)
Molecular Formula
C6H5BF2O2
Molecular Weight
157.91
MDL Number
MFCD01863170
PubChem ID
2734333
Melting Point
95 °C (dec.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
2,3-Difluorobenzeneboronic acid
CAS Number
121219-16-7
Purity
95 - 105% (Assay by titration)
Molecular Formula
C6H5BF2O2
Molecular Weight
157.91
MDL Number
MFCD01863170
PubChem ID
2734333
Melting Point
95 °C (dec.)
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,3-Difluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a crucial building block in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and other diseases. Its unique properties enhance the efficacy of drug candidates.
  • Organic Synthesis: It is employed in Suzuki-Miyaura cross-coupling reactions, allowing chemists to create complex organic molecules with precision. This application is vital in the production of agrochemicals and fine chemicals.
  • Material Science: The compound is used in the development of advanced materials, including polymers and nanomaterials, which have applications in electronics and coatings, providing improved durability and functionality.
  • Bioconjugation: It plays a significant role in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in drug delivery systems and diagnostic applications.
  • Research in Fluorinated Compounds: As a fluorinated boronic acid, it is valuable in studies exploring the properties and reactivity of fluorinated compounds, contributing to advancements in medicinal chemistry and materials research.

Citations