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Catalog Number:
40265
CAS Number:
848779-87-3
2-Benzyloxy-4-fluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
2-Benzyloxy-4-fluorobenzeneboronic acid
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Product Information

2-Benzyloxy-4-fluorophenylboronic acid is a versatile boronic acid derivative known for its significant applications in organic synthesis and medicinal chemistry. This compound features a unique combination of a fluorine atom and a benzyloxy group, making it an ideal candidate for cross-coupling reactions, particularly in the formation of carbon-carbon bonds. Its ability to act as a boron source allows for the development of complex molecules, which is crucial in the pharmaceutical industry for drug discovery and development. Researchers have utilized this compound in the synthesis of various biologically active compounds, showcasing its potential in creating novel therapeutic agents.

In addition to its synthetic utility, 2-Benzyloxy-4-fluorophenylboronic acid exhibits favorable properties that enhance its performance in various applications. Its stability and reactivity make it suitable for use in diverse chemical environments, allowing for flexibility in experimental designs. This compound stands out among similar boronic acids due to its specific functional groups, which can facilitate selective reactions and improve yields. As such, it is an invaluable tool for chemists looking to innovate in the fields of organic synthesis and drug development.

Synonyms
2-Benzyloxy-4-fluorobenzeneboronic acid
CAS Number
848779-87-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C13H12BFO3
Molecular Weight
246.04
MDL Number
MFCD03788402
PubChem ID
2782665
Melting Point
116 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-Benzyloxy-4-fluorobenzeneboronic acid
CAS Number
848779-87-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C13H12BFO3
Molecular Weight
246.04
MDL Number
MFCD03788402
PubChem ID
2782665
Melting Point
116 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Benzyloxy-4-fluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in developing drugs targeting cancer and other diseases due to its ability to form stable complexes with biomolecules.
  • Organic Synthesis: It is employed in cross-coupling reactions, such as Suzuki-Miyaura coupling, allowing chemists to create complex organic molecules efficiently, which is essential in materials science and drug discovery.
  • Bioconjugation: The boronic acid functionality enables selective binding to diols, making it valuable in bioconjugation techniques for labeling biomolecules, enhancing imaging and therapeutic applications in biotechnology.
  • Sensor Development: This compound can be used in the development of chemical sensors, particularly for detecting glucose levels, offering potential benefits in diabetes management through its selective binding properties.
  • Material Science: Its unique properties allow it to be incorporated into polymeric materials, improving their mechanical and thermal stability, which is beneficial in producing high-performance materials for various industrial applications.

Citations