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Catalog Number:
40262
CAS Number:
872460-12-3
3-Carboxy-4-fluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
3-Carboxy-4-fluorobenzeneboronic acid
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Product Information

3-Carboxy-4-fluorophenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its ability to form stable complexes with diols, making it an essential reagent in the development of various pharmaceuticals and agrochemicals. Its unique fluorine substitution enhances its reactivity and selectivity in cross-coupling reactions, particularly in Suzuki-Miyaura coupling, which is pivotal for constructing complex organic molecules. Researchers appreciate its role in the synthesis of biologically active compounds, including potential anticancer agents and other therapeutic molecules.

In addition to its synthetic applications, 3-Carboxy-4-fluorophenylboronic acid serves as a valuable tool in the field of materials science, particularly in the development of sensors and polymers. Its ability to interact with carbohydrates and other biomolecules opens avenues for innovative applications in biosensing and drug delivery systems. With its favorable properties and broad applicability, this compound stands out as a key ingredient for researchers and industry professionals aiming to advance their projects in organic synthesis and material development.

Synonyms
3-Carboxy-4-fluorobenzeneboronic acid
CAS Number
872460-12-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H6BFO4
Molecular Weight
183.93
MDL Number
MFCD03095129
PubChem ID
2763242
Melting Point
219 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
3-Carboxy-4-fluorobenzeneboronic acid
CAS Number
872460-12-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H6BFO4
Molecular Weight
183.93
MDL Number
MFCD03095129
PubChem ID
2763242
Melting Point
219 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-Carboxy-4-fluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound plays a crucial role in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and diabetes. Its ability to form stable complexes with biomolecules enhances drug efficacy.
  • Organic Synthesis: It is a valuable reagent in organic chemistry for the construction of complex molecules. Researchers use it in Suzuki coupling reactions, which are essential for creating biaryl compounds found in many natural products and pharmaceuticals.
  • Material Science: This chemical is used in the development of advanced materials, such as polymers and nanomaterials. Its unique properties allow for the modification of material surfaces, improving their performance in various applications.
  • Bioconjugation: In biochemistry, it is employed for labeling biomolecules. The boronic acid group can selectively bind to diols, making it useful for creating targeted drug delivery systems and diagnostic tools.
  • Environmental Monitoring: This compound can be utilized in the detection of environmental pollutants. Its chemical properties allow for the development of sensors that can identify specific contaminants in water and soil, contributing to environmental protection efforts.

Citations