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Catalog Number:
40253
CAS Number:
352535-97-8
3-Bromo-2-fluorophenylboronic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
3-Bromo-2-fluorobenzeneboronic acid
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Product Information

3-Bromo-2-fluorophenylboronic acid is a versatile organoboron compound that plays a crucial role in various chemical synthesis applications. This compound is particularly valued in the pharmaceutical and agrochemical industries for its ability to serve as a key building block in the development of biologically active molecules. Its unique structure allows for selective functionalization, making it an essential reagent in Suzuki-Miyaura cross-coupling reactions, which are widely used to form carbon-carbon bonds. Researchers appreciate its effectiveness in synthesizing complex organic compounds, including pharmaceuticals and advanced materials.

In addition to its synthetic utility, 3-Bromo-2-fluorophenylboronic acid exhibits excellent compatibility with various reaction conditions, enhancing its appeal for both academic and industrial applications. Its ability to facilitate the formation of diverse molecular architectures positions it as a valuable tool for chemists aiming to innovate in drug discovery and materials science. With its unique properties and broad applicability, this compound is an indispensable asset for professionals seeking to advance their research and development efforts.

Synonyms
3-Bromo-2-fluorobenzeneboronic acid
CAS Number
352535-97-8
Purity
≥ 98% (HPLC)
Molecular Formula
C6H5BBrFO2
Molecular Weight
218.82
MDL Number
MFCD05664228
PubChem ID
16217170
Melting Point
227 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
3-Bromo-2-fluorobenzeneboronic acid
CAS Number
352535-97-8
Purity
≥ 98% (HPLC)
Molecular Formula
C6H5BBrFO2
Molecular Weight
218.82
MDL Number
MFCD05664228
PubChem ID
16217170
Melting Point
227 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-Bromo-2-fluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and other diseases.
  • Organic Synthesis: It is employed in Suzuki coupling reactions, which are essential for forming carbon-carbon bonds in organic chemistry, facilitating the creation of complex molecules.
  • Material Science: The compound is used in the development of advanced materials, including polymers and nanomaterials, enhancing properties such as conductivity and strength.
  • Bioconjugation: It plays a role in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in diagnostics and therapeutic applications.
  • Fluorine Chemistry: The presence of fluorine in this compound makes it valuable for studies in fluorine chemistry, where it can be used to explore the effects of fluorine substitution on biological activity.

Citations