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Catalog Number:
40251
CAS Number:
505083-04-5
3-Fluoro-4-(methoxycarbonyl)phenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid
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Product Information

3-Fluoro-4-(methoxycarbonyl)phenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valuable in the development of pharmaceuticals and agrochemicals, where it serves as a key building block for the synthesis of various biologically active molecules. Its unique fluorine substituent enhances its reactivity and selectivity in cross-coupling reactions, making it an essential reagent for researchers aiming to create complex molecular architectures.

In addition to its applications in drug discovery, 3-Fluoro-4-(methoxycarbonyl)phenylboronic acid is also employed in the development of fluorescent probes and sensors, owing to its ability to form stable complexes with various substrates. This compound's favorable properties, such as its solubility in organic solvents and compatibility with a range of reaction conditions, make it an ideal choice for both academic and industrial laboratories. Researchers can leverage its unique characteristics to streamline their synthetic pathways and enhance the efficiency of their projects.

Synonyms
3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid
CAS Number
505083-04-5
Purity
97 - 105% (Assay by titration)
Molecular Formula
C8H8BFO4
Molecular Weight
197.96
MDL Number
MFCD04115665
PubChem ID
2782818
Melting Point
184 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
3-Fluoro-4-(methoxycarbonyl)benzeneboronic acid
CAS Number
505083-04-5
Purity
97 - 105% (Assay by titration)
Molecular Formula
C8H8BFO4
Molecular Weight
197.96
MDL Number
MFCD04115665
PubChem ID
2782818
Melting Point
184 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-Fluoro-4-(methoxycarbonyl)phenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-cancer agents. Its unique structure allows for targeted modifications that enhance drug efficacy.
  • Organic Synthesis: It is employed in cross-coupling reactions, such as Suzuki-Miyaura coupling, which are essential for constructing complex organic molecules. This application is vital in the creation of new materials and compounds in the chemical industry.
  • Bioconjugation: The boronic acid functionality enables the formation of stable bonds with diols, making it useful in bioconjugation processes for developing targeted drug delivery systems and diagnostic tools.
  • Material Science: This compound can be used in the synthesis of functionalized polymers and materials, which are important in creating advanced materials with specific properties for electronics and coatings.
  • Research in Catalysis: It plays a role in catalysis research, particularly in the development of new catalytic systems that improve reaction efficiency and selectivity in various chemical processes.

Citations