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Catalog Number:
40243
CAS Number:
851335-07-4
4-Carboxy-2-fluorophenylboronic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
4-Carboxy-2-fluorobenzeneboronic acid
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Product Information

4-Carboxy-2-fluorophenylboronic acid is a versatile compound that plays a significant role in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its ability to form stable complexes with diols, making it an essential reagent in the development of various pharmaceuticals and agrochemicals. Its unique fluorine substitution enhances its reactivity and selectivity, allowing for more efficient synthesis pathways in the creation of complex molecular structures. Researchers have utilized this compound in the synthesis of biologically active molecules, particularly in the development of targeted therapies and drug candidates.

In addition to its applications in drug discovery, 4-Carboxy-2-fluorophenylboronic acid is also valuable in materials science, where it can be employed in the fabrication of advanced materials and sensors. Its ability to participate in cross-coupling reactions, such as Suzuki-Miyaura coupling, further expands its utility in creating functionalized organic compounds. With its favorable properties and broad applicability, this compound is an excellent choice for researchers and industry professionals looking to enhance their synthetic methodologies and develop innovative solutions.

Synonyms
4-Carboxy-2-fluorobenzeneboronic acid
CAS Number
851335-07-4
Purity
≥ 98% (HPLC)
Molecular Formula
C7H6BFO4
Molecular Weight
183.93
MDL Number
MFCD08458473
PubChem ID
23134177
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-Carboxy-2-fluorobenzeneboronic acid
CAS Number
851335-07-4
Purity
≥ 98% (HPLC)
Molecular Formula
C7H6BFO4
Molecular Weight
183.93
MDL Number
MFCD08458473
PubChem ID
23134177
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Carboxy-2-fluorophenylboronic acid is widely utilized in research focused on:

  • Drug Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of targeted cancer therapies that require precise molecular interactions.
  • Bioconjugation: It is used in bioconjugation processes to attach biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the efficacy of diagnostic tools and therapeutic agents.
  • Organic Synthesis: The compound plays a significant role in organic synthesis as a building block for creating complex organic molecules, which are essential in materials science and chemical manufacturing.
  • Fluorescent Probes: Due to its unique fluorine atom, it is utilized in the development of fluorescent probes for biological imaging, allowing researchers to visualize cellular processes in real-time.
  • Environmental Monitoring: This chemical is also applied in environmental science for detecting and quantifying pollutants, contributing to efforts in maintaining ecological safety and compliance with regulations.

Citations