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Catalog Number:
40236
CAS Number:
89694-46-2
2-Chloro-5-methoxyphenylboronic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
2-Chloro-5-methoxybenzeneboronic acid
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Product Information

2-Chloro-5-methoxyphenylboronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Its unique structure, featuring a chloro and methoxy group, enhances its reactivity and selectivity, allowing researchers to create targeted compounds with improved efficacy.

In addition to its synthetic applications, 2-Chloro-5-methoxyphenylboronic acid has shown potential in the development of novel materials and sensors, particularly in the field of biosensing where its boronic acid functionality can interact with diols, enabling the detection of sugars and other biomolecules. This compound is particularly advantageous for researchers seeking to streamline their synthesis processes while maintaining high yields and purity. Its compatibility with various reaction conditions further solidifies its position as a valuable tool in both academic and industrial laboratories.

Synonyms
2-Chloro-5-methoxybenzeneboronic acid
CAS Number
89694-46-2
Purity
≥ 98% (HPLC)
Molecular Formula
C7H8BClO3
Molecular Weight
186.4
MDL Number
MFCD06659858
PubChem ID
17750233
Melting Point
115 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
2-Chloro-5-methoxybenzeneboronic acid
CAS Number
89694-46-2
Purity
≥ 98% (HPLC)
Molecular Formula
C7H8BClO3
Molecular Weight
186.4
MDL Number
MFCD06659858
PubChem ID
17750233
Melting Point
115 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Chloro-5-methoxyphenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound plays a crucial role in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and other diseases. Its ability to form stable complexes with biomolecules enhances drug efficacy.
  • Organic Synthesis: It serves as a key reagent in Suzuki coupling reactions, allowing chemists to create complex organic molecules efficiently. This is particularly valuable in the production of agrochemicals and fine chemicals.
  • Material Science: The compound is used in the development of advanced materials, including polymers and nanomaterials, which have applications in electronics and coatings, offering improved performance and durability.
  • Bioconjugation: Its boronic acid functionality allows for selective binding to diols, making it useful in bioconjugation techniques for labeling biomolecules, which is essential in diagnostics and research.
  • Environmental Chemistry: This compound can be employed in the detection and removal of pollutants, as it can form complexes with certain environmental contaminants, aiding in the development of remediation strategies.

Citations