Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
40229
CAS Number:
444666-39-1
2-Chloro-5-fluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
2-Chloro-5-fluorobenzeneboronic acid
Documents
$130.60 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

2-Chloro-5-fluorophenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Its unique combination of a chlorine and fluorine substituent enhances its reactivity and selectivity, allowing for the development of targeted compounds with improved efficacy. Researchers have successfully employed this compound in the synthesis of various biologically active molecules, showcasing its potential in drug discovery and development.

In addition to its applications in synthetic organic chemistry, 2-Chloro-5-fluorophenylboronic acid serves as a crucial intermediate in the production of fluorescent probes and sensors, which are vital in biochemical research and diagnostics. Its ability to form stable complexes with various substrates makes it an attractive option for researchers looking to innovate in the fields of material science and biochemistry. With its proven track record and diverse applications, this compound is an invaluable asset for professionals seeking to advance their projects in chemical synthesis and research.

Synonyms
2-Chloro-5-fluorobenzeneboronic acid
CAS Number
444666-39-1
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD06656272
PubChem ID
22648116
Melting Point
82 °C (Lit.)
Appearance
White to off white crystalline powder
Conditions
Store at RT
General Information
Synonyms
2-Chloro-5-fluorobenzeneboronic acid
CAS Number
444666-39-1
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BClFO2
Molecular Weight
174.36
MDL Number
MFCD06656272
PubChem ID
22648116
Melting Point
82 °C (Lit.)
Appearance
White to off white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Chloro-5-fluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of targeted cancer therapies.
  • Organic Synthesis: It is commonly used in Suzuki coupling reactions, which are essential for forming carbon-carbon bonds in organic compounds, making it valuable for creating complex molecules.
  • Material Science: The compound is employed in the production of advanced materials, including polymers and coatings, enhancing properties such as durability and chemical resistance.
  • Bioconjugation: Its boronic acid functionality allows for selective binding to diols, making it useful in bioconjugation applications, such as labeling biomolecules for imaging or therapeutic purposes.
  • Environmental Chemistry: This chemical is also investigated for its potential in environmental applications, such as the removal of pollutants from water through boron-based adsorbents.

Citations