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Catalog Number:
40221
CAS Number:
913835-75-3
5-Carboxy-2-chlorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
5-Carboxy-2-chlorobenzeneboronic acid
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Product Information

5-Carboxy-2-chlorophenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its ability to form stable complexes with diols, making it an essential reagent in the development of various pharmaceuticals and agrochemicals. Its unique structure allows it to participate in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds, which is crucial in the synthesis of complex organic molecules. Researchers and industry professionals appreciate its role in the development of targeted therapies, particularly in oncology, where it aids in the design of boron-containing drugs that can enhance the efficacy of treatments.

Additionally, 5-Carboxy-2-chlorophenylboronic acid is employed in the preparation of sensor materials due to its selective binding properties. Its applications extend to the production of advanced materials and in the field of biochemistry, where it is used for the detection of sugars and other biomolecules. With its high reactivity and specificity, this compound stands out as a valuable tool for researchers aiming to innovate in drug development and material science.

Synonyms
5-Carboxy-2-chlorobenzeneboronic acid
CAS Number
913835-75-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H6BClO4
Molecular Weight
200.38
MDL Number
MFCD08689491
PubChem ID
17750228
Melting Point
244 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
5-Carboxy-2-chlorobenzeneboronic acid
CAS Number
913835-75-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C7H6BClO4
Molecular Weight
200.38
MDL Number
MFCD08689491
PubChem ID
17750228
Melting Point
244 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Carboxy-2-chlorophenylboronic acid is widely utilized in research focused on:

  • Drug Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in developing targeted cancer therapies that require boron-containing compounds for enhanced efficacy.
  • Organic Synthesis: It is used in Suzuki-Miyaura cross-coupling reactions, allowing chemists to create complex organic molecules efficiently, which is crucial in materials science and agrochemicals.
  • Bioconjugation: The unique reactivity of this boronic acid makes it suitable for attaching biomolecules, such as proteins or nucleic acids, which is essential in creating biopharmaceuticals and diagnostics.
  • Sensor Development: This compound is employed in the design of chemical sensors for detecting glucose and other biomolecules, offering advantages in diabetes management and biomedical research.
  • Polymer Chemistry: It is utilized in the formulation of smart polymers that respond to environmental stimuli, which can be applied in drug delivery systems and responsive materials for various industries.

Citations