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Catalog Number:
40216
CAS Number:
175883-63-3
3-Chloro-4-methylphenylboronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
3-Chloro-4-methylbenzeneboronic acid, 3-Chloro-p-tolylboronic acid
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Product Information

3-Chloro-4-methylphenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Its unique chloromethyl and boronic acid functional groups enhance its reactivity and selectivity, allowing researchers to develop targeted compounds with improved efficacy.

In addition to its applications in synthetic chemistry, 3-Chloro-4-methylphenylboronic acid has shown potential in the development of novel materials and sensors. Its ability to form stable complexes with various substrates opens avenues for innovative research in catalysis and bioconjugation. Researchers and industry professionals can leverage this compound to streamline their synthesis processes and enhance the performance of their products, making it a valuable addition to any laboratory focused on advanced chemical research.

Synonyms
3-Chloro-4-methylbenzeneboronic acid, 3-Chloro-p-tolylboronic acid
CAS Number
175883-63-3
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H8BClO2
Molecular Weight
170.4
MDL Number
MFCD04039010
PubChem ID
3854610
Melting Point
247 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
3-Chloro-4-methylbenzeneboronic acid, 3-Chloro-p-tolylboronic acid
CAS Number
175883-63-3
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H8BClO2
Molecular Weight
170.4
MDL Number
MFCD04039010
PubChem ID
3854610
Melting Point
247 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-Chloro-4-methylphenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a key building block in the synthesis of various organic molecules, particularly in the development of pharmaceuticals and agrochemicals.
  • Cross-Coupling Reactions: It is commonly used in Suzuki-Miyaura coupling reactions, which are essential for forming carbon-carbon bonds in complex organic compounds, enhancing efficiency in chemical manufacturing.
  • Drug Development: Researchers leverage its properties to create novel drug candidates, particularly in oncology, where boronic acids have shown promise in targeting specific cancer pathways.
  • Material Science: The compound finds applications in developing advanced materials, such as polymers and nanomaterials, due to its ability to form stable complexes with various substrates.
  • Analytical Chemistry: It is used in the development of sensors and probes for detecting biomolecules, offering high sensitivity and specificity in various analytical applications.

Citations