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Catalog Number:
31443
CAS Number:
144025-03-6
2,4-Difluorophenylboronic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
2,4-Difluorobenzeneboronic acid, (2,4-Difluorophenyl)boranediol
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Product Information

2,4-Difluorophenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its unique ability to form stable complexes with diols, making it an essential reagent in the development of various pharmaceuticals and agrochemicals. Its distinct fluorine substituents enhance its reactivity and selectivity in cross-coupling reactions, particularly in Suzuki-Miyaura coupling, which is crucial for constructing complex organic molecules. Researchers appreciate its role in the synthesis of biologically active compounds, including potential drug candidates that target specific diseases.

In addition to its applications in synthetic chemistry, 2,4-Difluorophenylboronic acid serves as a valuable tool in the development of sensors and materials science. Its ability to interact with carbohydrates and other biomolecules opens avenues for innovative biosensor technologies. With its favorable properties and diverse applications, this compound stands out as a key player in advancing research and industrial processes, providing significant advantages over similar boronic acids in terms of reactivity and specificity.

Synonyms
2,4-Difluorobenzeneboronic acid, (2,4-Difluorophenyl)boranediol
CAS Number
144025-03-6
Purity
≥ 99% (HPLC)
Molecular Formula
C6H5BF2O2
Molecular Weight
157.91
MDL Number
MFCD01318998
PubChem ID
2734334
Melting Point
247 - 250 ?C
Appearance
Off-white to white powder
Conditions
Store at RT
General Information
Synonyms
2,4-Difluorobenzeneboronic acid, (2,4-Difluorophenyl)boranediol
CAS Number
144025-03-6
Purity
≥ 99% (HPLC)
Molecular Formula
C6H5BF2O2
Molecular Weight
157.91
MDL Number
MFCD01318998
PubChem ID
2734334
Melting Point
247 - 250 ?C
Appearance
Off-white to white powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,4-Difluorophenylboronic acid is widely utilized in research focused on:

  • Medicinal Chemistry: This compound serves as a crucial building block in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and diabetes. Its unique structure allows for enhanced interactions with biological targets.
  • Organic Synthesis: It is employed in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds. This application is essential for creating complex organic molecules in the pharmaceutical and agrochemical industries.
  • Material Science: The compound is used in the development of advanced materials, including polymers and composites, that exhibit improved thermal and mechanical properties, making them suitable for high-performance applications.
  • Diagnostics: 2,4-Difluorophenylboronic acid is utilized in the design of sensors for detecting biomolecules, offering high sensitivity and selectivity, which is vital for medical diagnostics and environmental monitoring.
  • Research and Development: It plays a significant role in academic and industrial research settings, where its unique properties enable scientists to explore new chemical reactions and develop innovative solutions to complex problems.

Citations