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Catalog Number:
31438
CAS Number:
352303-67-4
2-Fluoro-3-methoxyphenylboronic acid
Purity:
≥ 99.5% (HPLC)
Synonym(s):
2-Fluoro-3-methoxybenzeneboronic acid
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Product Information

2-Fluoro-3-methoxyphenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its ability to form stable complexes with diols, making it an essential reagent in Suzuki-Miyaura cross-coupling reactions. Researchers and industry professionals leverage its unique properties to create complex organic molecules, particularly in the development of pharmaceuticals and agrochemicals. Its fluorine and methoxy substituents enhance its reactivity and selectivity, allowing for more efficient synthesis pathways compared to traditional boronic acids.

In addition to its applications in synthetic chemistry, 2-Fluoro-3-methoxyphenylboronic acid has shown promise in the field of materials science, where it can be used to modify surfaces and create functionalized polymers. Its compatibility with various reaction conditions makes it a valuable tool for chemists seeking to innovate and optimize their processes. With its growing importance in research and industry, this compound stands out as a key player in advancing chemical synthesis and material development.

Synonyms
2-Fluoro-3-methoxybenzeneboronic acid
CAS Number
352303-67-4
Purity
≥ 99.5% (HPLC)
Molecular Formula
C7H8BFO3
Molecular Weight
169.95
MDL Number
MFCD02094728
PubChem ID
4985744
Melting Point
117 - 122 ?C
Appearance
Off-white solid
Conditions
Store at RT
General Information
Synonyms
2-Fluoro-3-methoxybenzeneboronic acid
CAS Number
352303-67-4
Purity
≥ 99.5% (HPLC)
Molecular Formula
C7H8BFO3
Molecular Weight
169.95
MDL Number
MFCD02094728
PubChem ID
4985744
Melting Point
117 - 122 ?C
Appearance
Off-white solid
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Fluoro-3-methoxyphenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and other diseases. Its unique structure allows for the modification of biological activity, making it valuable in drug discovery.
  • Organic Synthesis: It is frequently used in cross-coupling reactions, such as Suzuki-Miyaura coupling, which is essential for forming carbon-carbon bonds. This application is crucial in creating complex organic molecules, thereby enhancing the efficiency of synthetic pathways.
  • Material Science: The compound is employed in the development of advanced materials, including polymers and nanomaterials. Its boronic acid functionality allows for the formation of dynamic covalent bonds, which can improve material properties like strength and flexibility.
  • Bioconjugation: In biochemistry, it is utilized for the modification of biomolecules, enabling the attachment of various functional groups. This application is particularly important in creating targeted drug delivery systems and diagnostic tools.
  • Analytical Chemistry: It is used in the development of sensors and assays for detecting specific biomolecules. The ability to form stable complexes with certain analytes enhances the sensitivity and selectivity of these analytical methods.

Citations