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Catalog Number:
27556
CAS Number:
5720-07-0
4-Methoxyphenylboronic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
(4-Methoxyphenyl)boranediol, p-Anisylboronic acid
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Product Information

4-Methoxyphenylboronic acid is a versatile organoboron compound widely utilized in organic synthesis and medicinal chemistry. This compound features a methoxy group that enhances its solubility and reactivity, making it an excellent choice for cross-coupling reactions, particularly in the development of pharmaceuticals and agrochemicals. Its ability to form stable complexes with various substrates allows for efficient catalysis in Suzuki-Miyaura reactions, which are crucial for constructing complex molecular architectures. Researchers appreciate its role in the synthesis of biologically active compounds, including potential drug candidates, due to its compatibility with a range of functional groups.

In addition to its synthetic applications, 4-Methoxyphenylboronic acid is also employed in the development of sensors and materials science, where its boronic acid functionality can interact with diols and sugars, making it valuable for glucose sensing applications. Its unique properties, such as high reactivity and selectivity, make it a preferred choice for chemists looking to streamline their synthetic pathways while achieving high yields. Overall, this compound stands out for its practicality and effectiveness in various industrial and research applications.

Synonyms
(4-Methoxyphenyl)boranediol, p-Anisylboronic acid
CAS Number
5720-07-0
Purity
≥ 98% (HPLC)
Molecular Formula
C7H9BO3
Molecular Weight
151.96
MDL Number
MFCD00039139
PubChem ID
201262
Melting Point
200 - 209 ?C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
(4-Methoxyphenyl)boranediol, p-Anisylboronic acid
CAS Number
5720-07-0
Purity
≥ 98% (HPLC)
Molecular Formula
C7H9BO3
Molecular Weight
151.96
MDL Number
MFCD00039139
PubChem ID
201262
Melting Point
200 - 209 ?C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Methoxyphenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a key reagent in the Suzuki coupling reaction, enabling the formation of carbon-carbon bonds. This is particularly valuable in the synthesis of pharmaceuticals and agrochemicals.
  • Bioconjugation: It is used to create boronate esters, which can selectively bind to diols in biological molecules. This application is crucial in developing targeted drug delivery systems and biomolecular labeling.
  • Sensor Development: The compound is employed in the design of chemical sensors for detecting glucose and other sugars, benefiting the medical field by aiding in diabetes management.
  • Material Science: It is utilized in the development of polymeric materials with enhanced properties, such as increased thermal stability and mechanical strength, which are essential in various industrial applications.
  • Research in Medicinal Chemistry: Its role in modifying drug structures can lead to improved efficacy and reduced side effects, making it a valuable tool in the development of new therapeutic agents.

Citations