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Catalog Number:
17020
CAS Number:
182344-18-9
2-Chloro-5-(trifluoromethyl)phenylboronic acid
Purity:
≥ 99%
Synonym(s):
2-Chloro-5-(trifluoromethyl)benzeneboronic acid
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Product Information

2-Chloro-5-(trifluoromethyl)phenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the synthesis of complex organic molecules. Its unique trifluoromethyl group enhances the compound's lipophilicity and stability, which is particularly beneficial in the development of pharmaceuticals and agrochemicals. Researchers appreciate its role in the formation of carbon-carbon bonds, enabling the creation of diverse compounds with potential applications in drug discovery and material science.

In addition to its synthetic utility, 2-Chloro-5-(trifluoromethyl)phenylboronic acid is noted for its effectiveness in targeting specific biological pathways, which can lead to the development of novel therapeutic agents. Its distinct properties allow for selective interactions in biological systems, making it a valuable tool in medicinal chemistry. With its robust performance in various applications, this compound stands out as a reliable choice for researchers and industry professionals seeking to innovate and enhance their chemical processes.

Synonyms
2-Chloro-5-(trifluoromethyl)benzeneboronic acid
CAS Number
182344-18-9
Purity
≥ 99%
Molecular Formula
C7H5BClF3O2
Molecular Weight
224.37
MDL Number
MFCD00797335
PubChem ID
2782670
Appearance
White powder
Conditions
Store at 0-8°C
General Information
Synonyms
2-Chloro-5-(trifluoromethyl)benzeneboronic acid
CAS Number
182344-18-9
Purity
≥ 99%
Molecular Formula
C7H5BClF3O2
Molecular Weight
224.37
MDL Number
MFCD00797335
PubChem ID
2782670
Appearance
White powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Chloro-5-(trifluoromethyl)phenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and other diseases.
  • Organic Synthesis: It is employed in cross-coupling reactions, such as Suzuki-Miyaura coupling, to create complex organic molecules, making it invaluable in the field of organic chemistry.
  • Material Science: The compound is used in the preparation of advanced materials, including polymers and coatings, due to its unique chemical properties that enhance material performance.
  • Agricultural Chemistry: It plays a role in the development of agrochemicals, contributing to the formulation of effective pesticides and herbicides that improve crop yields.
  • Analytical Chemistry: This boronic acid derivative is utilized in sensor technology for detecting sugars and other biomolecules, aiding in various analytical applications.

Citations