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Catalog Number:
16980
CAS Number:
444120-91-6
2-Chloropyridine-5-boronic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
6-Chloro-3-pyridineboronic acid
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Product Information

2-Chloropyridine-5-boronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the formation of biaryl compounds, which are significant in pharmaceuticals and agrochemicals. Its unique chloropyridine structure enhances its reactivity and selectivity, allowing researchers to create complex molecules with precision.

In addition to its synthetic applications, 2-Chloropyridine-5-boronic acid is also utilized in the development of various biologically active compounds, including those targeting cancer and other diseases. Its compatibility with various functional groups and ease of use in laboratory settings make it a preferred choice for chemists looking to streamline their synthesis processes. With its proven track record in enhancing reaction efficiency and yield, this compound stands out as a valuable asset in both research and industrial applications.

Synonyms
6-Chloro-3-pyridineboronic acid
CAS Number
444120-91-6
Purity
≥ 99% (HPLC)
Molecular Formula
C5H5BClNO2
Molecular Weight
157.36
MDL Number
MFCD03094998
PubChem ID
3845034
Appearance
Off-white solid
Conditions
Store at 0-8°C
General Information
Synonyms
6-Chloro-3-pyridineboronic acid
CAS Number
444120-91-6
Purity
≥ 99% (HPLC)
Molecular Formula
C5H5BClNO2
Molecular Weight
157.36
MDL Number
MFCD03094998
PubChem ID
3845034
Appearance
Off-white solid
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Chloropyridine-5-boronic acid is widely utilized in research focused on:

  • Synthetic Chemistry: This compound serves as a key building block in the synthesis of various pharmaceuticals and agrochemicals, enabling the creation of complex molecular structures efficiently.
  • Cross-Coupling Reactions: It is particularly valuable in Suzuki-Miyaura coupling reactions, which allow for the formation of carbon-carbon bonds, essential in developing new materials and drugs.
  • Bioconjugation: The boronic acid functionality enables selective binding to diols, making it useful in bioconjugation techniques for labeling biomolecules in research and diagnostics.
  • Material Science: This compound is used in the development of advanced materials, such as sensors and polymers, due to its ability to form stable complexes with various substrates.
  • Medicinal Chemistry: It plays a role in the design of inhibitors for certain enzymes, contributing to the development of targeted therapies in cancer treatment and other diseases.

Citations