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Catalog Number:
23049
CAS Number:
125559-00-4
N-Succinimidyl 6-[[4-(maleimidomethyl)cyclohexyl]carboxamido]caproate
Purity:
≥ 98% (Assay)
Synonym(s):
LC-SMCC
Documents
$134.70 /25MG
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Product Information

N-Succinimidyl 6-[[4-(maleimidomethyl)cyclohexyl]carboxamido]caproate is a versatile compound widely utilized in bioconjugation and drug delivery applications. This compound features a unique maleimide functionality, which allows for selective conjugation to thiol-containing biomolecules, making it an essential tool for researchers in the fields of biochemistry and molecular biology. Its structure promotes stability and solubility, enhancing its effectiveness in various experimental setups.

In practical applications, N-Succinimidyl 6-[[4-(maleimidomethyl)cyclohexyl]carboxamido]caproate is often employed in the development of targeted therapeutics and diagnostic agents, facilitating the attachment of drugs or imaging agents to specific proteins or antibodies. This specificity can lead to improved efficacy and reduced side effects in therapeutic applications. Additionally, its use in the creation of antibody-drug conjugates (ADCs) exemplifies its potential in advancing cancer treatment strategies. Researchers can leverage this compound to enhance the precision of their studies and the effectiveness of their therapeutic designs.

Synonyms
LC-SMCC
CAS Number
125559-00-4
Purity
≥ 98% (Assay)
Molecular Formula
C22H29N3O7
Molecular Weight
447.44
MDL Number
MFCD01863459
PubChem ID
3564731
Melting Point
169 - 181 °C
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
LC-SMCC
CAS Number
125559-00-4
Purity
≥ 98% (Assay)
Molecular Formula
C22H29N3O7
Molecular Weight
447.44
MDL Number
MFCD01863459
PubChem ID
3564731
Melting Point
169 - 181 °C
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-Succinimidyl 6-[[4-(maleimidomethyl)cyclohexyl]carboxamido]caproate is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a versatile linker for attaching biomolecules, such as proteins or antibodies, to various surfaces or other molecules, enhancing the development of targeted therapies.
  • Drug Delivery Systems: Its ability to form stable conjugates makes it ideal for creating drug delivery systems that improve the efficacy and specificity of therapeutic agents, particularly in cancer treatment.
  • Diagnostic Applications: The chemical is used in the preparation of imaging agents, allowing for better visualization of biological processes in vivo, which is crucial in medical diagnostics.
  • Protein Engineering: Researchers utilize this compound to modify proteins, enabling the study of protein interactions and functions, which is essential in understanding biological mechanisms.
  • Vaccine Development: It plays a role in the formulation of vaccines by facilitating the conjugation of antigens to carrier proteins, improving immune responses and vaccine stability.

Citations