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Catalog Number:
23025
CAS Number:
68528-80-3
Disuccinimidyl suberate
Purity:
≥ 99% (NMR)
Synonym(s):
DSS, Disuccinimidyl octanedioate, Suberic acid bis(N-hydroxysuccinimide ester)
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$134.70 /1G
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Product Information

Disuccinimidyl suberate is a versatile crosslinking agent widely utilized in bioconjugation and protein chemistry. This compound is particularly valued for its ability to form stable amide bonds, making it an excellent choice for linking proteins, peptides, and other biomolecules. Its unique structure allows for the efficient formation of crosslinked networks, which can enhance the stability and functionality of various biological systems. Researchers often employ disuccinimidyl suberate in the development of targeted drug delivery systems, where it aids in the conjugation of therapeutic agents to antibodies or other targeting moieties, thereby improving the efficacy of treatments.

In addition to its applications in drug development, disuccinimidyl suberate is also used in the creation of biomaterials and in the study of protein interactions. Its ability to facilitate the formation of covalent bonds under mild conditions makes it a preferred choice for many laboratory protocols. The compound's compatibility with a range of functional groups further expands its utility in various research and industrial applications, providing a reliable solution for scientists looking to enhance their experimental outcomes.

Synonyms
DSS, Disuccinimidyl octanedioate, Suberic acid bis(N-hydroxysuccinimide ester)
CAS Number
68528-80-3
Purity
≥ 99% (NMR)
Molecular Formula
C16H20N2O8
Molecular Weight
368.34
MDL Number
MFCD00049059
PubChem ID
100658
Melting Point
167-172 °C
Appearance
White solid
Conditions
Store at ≤ -4 °C
General Information
Synonyms
DSS, Disuccinimidyl octanedioate, Suberic acid bis(N-hydroxysuccinimide ester)
CAS Number
68528-80-3
Purity
≥ 99% (NMR)
Molecular Formula
C16H20N2O8
Molecular Weight
368.34
MDL Number
MFCD00049059
PubChem ID
100658
Melting Point
167-172 °C
Appearance
White solid
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Disuccinimidyl suberate is widely utilized in research focused on:

  • Protein Crosslinking: This compound is commonly used to create stable crosslinks between proteins, which is essential in studying protein interactions and structures.
  • Bioconjugation: It facilitates the attachment of biomolecules, such as antibodies to drugs or imaging agents, enhancing their efficacy in targeted therapies and diagnostics.
  • Vaccine Development: In vaccine research, it helps in the conjugation of antigens to carrier proteins, improving immune responses and vaccine stability.
  • Cellular Studies: Researchers use it to crosslink cellular components, allowing for detailed studies of cellular mechanisms and signaling pathways.
  • Material Science: It is applied in the development of biomaterials, providing enhanced mechanical properties and biocompatibility for medical implants and devices.

Citations