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Catalog Number:
07339
CAS Number:
214475-53-3
Fmoc-4-hydrazinobenzoic acid
Purity:
≥ 95% (HPLC)
Synonym(s):
4-(Fmoc-hydrazino)-benzoic acid
Documents
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Product Information

Fmoc-4-hydrazinobenzoic acid is a versatile compound widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during the synthesis of peptides. Its unique structure allows for efficient coupling reactions, making it an invaluable tool for researchers in the development of peptide-based therapeutics. The hydrazine functional group enhances its reactivity, facilitating the formation of hydrazones and other derivatives that are crucial in drug discovery and development.

In addition to its applications in peptide synthesis, Fmoc-4-hydrazinobenzoic acid is also explored for its potential in the development of novel materials and as a building block in organic synthesis. Its ability to form stable complexes with metal ions opens avenues for applications in catalysis and materials science. Researchers appreciate its ease of use and the high yields it provides in various reactions, making it a preferred choice for both academic and industrial applications.

Synonyms
4-(Fmoc-hydrazino)-benzoic acid
CAS Number
214475-53-3
Purity
≥ 95% (HPLC)
Molecular Formula
C22H18N2O4
Molecular Weight
374.4
MDL Number
MFCD02179643
PubChem ID
2756155
Appearance
Off-white to light grey solid
Conditions
Store at 0 - 8 °C
General Information
Synonyms
4-(Fmoc-hydrazino)-benzoic acid
CAS Number
214475-53-3
Purity
≥ 95% (HPLC)
Molecular Formula
C22H18N2O4
Molecular Weight
374.4
MDL Number
MFCD02179643
PubChem ID
2756155
Appearance
Off-white to light grey solid
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-hydrazinobenzoic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the introduction of hydrazine functionalities.
  • Drug Development: It is used in the design of novel pharmaceutical compounds, especially those targeting specific biological pathways, due to its ability to form stable conjugates with various biomolecules.
  • Bioconjugation: The chemical is effective in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is crucial in the development of targeted drug delivery systems.
  • Diagnostic Applications: It finds applications in the creation of diagnostic agents, particularly in imaging techniques where specific targeting of cells or tissues is required.
  • Research in Cancer Therapeutics: The compound is being explored for its potential in cancer research, particularly in the development of hydrazine-based prodrugs that can selectively target cancer cells.

Citations