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Catalog Number:
23004
CAS Number:
51805-45-9
Tris-(carboxyethyl)phosphine hydrochloride  
Purity:
≥ 98% (Assay by titration)
Synonym(s):
TCEP·HCl
Hazmat
Documents
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Product Information

Tris-(carboxyethyl)phosphine hydrochloride is a versatile and highly effective reducing agent widely utilized in various chemical and biochemical applications. This compound is particularly valued for its ability to selectively reduce disulfides to thiols, making it an essential tool in protein chemistry and bioconjugation processes. Its unique structure allows for enhanced stability and solubility in aqueous environments, which is crucial for applications in biological systems. Researchers often employ this compound in the synthesis of thiol-containing compounds, facilitating the study of protein folding, stability, and interactions.

In addition to its role in protein chemistry, Tris-(carboxyethyl)phosphine hydrochloride is also utilized in the synthesis of nanoparticles and in the field of organic synthesis for the reduction of various functional groups. Its effectiveness in reducing metal ions to their elemental forms makes it a valuable reagent in materials science. The compound's ease of use and compatibility with a wide range of substrates further enhance its appeal to researchers and industry professionals alike, providing a reliable solution for complex chemical transformations.

Synonyms
TCEP·HCl
CAS Number
51805-45-9
Purity
≥ 98% (Assay by titration)
Molecular Formula
C9H15O6P·HCl
Molecular Weight
286.6
MDL Number
MFCD00145469
PubChem ID
2734570
Melting Point
176 - 186 ?C
Appearance
White crystal
Conditions
Store at 0 - 8 °C under Nitrogen
Warnings
Danger
General Information
Synonyms
TCEP·HCl
CAS Number
51805-45-9
Purity
≥ 98% (Assay by titration)
Molecular Formula
C9H15O6P·HCl
Molecular Weight
286.6
MDL Number
MFCD00145469
PubChem ID
2734570
Melting Point
176 - 186 ?C
Appearance
White crystal
Conditions
Store at 0 - 8 °C under Nitrogen
Warnings
Danger
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
Danger
Applications

Tris-(carboxyethyl)phosphine hydrochloride is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a reducing agent in the synthesis of bioconjugates, enhancing the stability and functionality of biomolecules for drug development.
  • Antioxidant Applications: Its antioxidant properties make it valuable in protecting cells from oxidative stress, which is particularly beneficial in pharmaceutical formulations aimed at treating age-related diseases.
  • Protein Chemistry: It is used in protein labeling and modification processes, allowing researchers to study protein interactions and functions more effectively.
  • Analytical Chemistry: The compound aids in the detection and quantification of various biomolecules, improving the accuracy of analytical methods in laboratories.
  • Material Science: In the development of new materials, it acts as a stabilizing agent, enhancing the durability and performance of polymers and coatings.

Citations